220873-36-9

Basic information

• Product Name: 3-(6-benzyloxy-1H-indol-3-yl)-1-benzyloxymethyl-4-bromo-pyrrole-2,5-dione
• CAS NO: 220873-36-9
• Molecular Weight: 517.379
• Mol File: 220873-36-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(6-benzyloxy-1H-indol-3-yl)-1-benzyloxymethyl-4-bromo-pyrrole-2,5-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(6-benzyloxy-1H-indol-3-yl)-1-benzyloxymethyl-4-bromo-pyrrole-2,5-dione(220873-36-9)
• EPA Substance Registry System: 3-(6-benzyloxy-1H-indol-3-yl)-1-benzyloxymethyl-4-bromo-pyrrole-2,5-dione(220873-36-9)

Safety Data

• Hazardous Substances Data: 220873-36-9(Hazardous Substances Data)

Upstream product

• 15903-94-3 6-benzyloxy-1H-indole 
• 102147-52-4 N-benzyloxymethyl-3,4-dibromomaleimide 

Downstream Products

• 220873-42-7 3-(6-Benzyloxy-1H-indol-3-yl)-1-benzyloxymethyl-4-[6-benzyloxy-1-((2R,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-1H-indol-3-yl]-pyrrole-2,5-dione 
• 220873-39-2 1-Benzyloxymethyl-3-[6-benzyloxy-1-((2R,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-1H-indol-3-yl]-4-bromo-pyrrole-2,5-dione 

Relevant articles and documents

Indolocarbazole poisons of human topoisomerase I: Regioisomeric analogues of ED-110

All four 'symmetrical' regioisomers of ED-110, an indolocarbazole derivative having potent activity against human topoisomerase I (Topo I) were synthesized. The isomer containing hydroxyl groups in the 3- and 9-positions was approximately ten-fold more active against Topo I, and 5- to 35-fold more active against human solid tumor cell lines in vitro, relative to ED-110.