220895-45-4Relevant articles and documents
Oxindolylquinazoline derivatives as angiogenesis inhibitors
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, (2008/06/13)
The invention relates to compounds of formula (I) and salts thereof as further defined herein, wherein ring Z is a 6-membered heterocyclic ring containing 1 to 3 nitrogen atoms, and the use of such compounds and salts to inhibit the effects of VEGF and FGF, and in the treatment of a number of disease states including cancer and rheumatoid arthritis.