2209-25-8

Basic information

• Product Name: 1-(p-tolyl)-3-(p-tolylcarbamothioylamino)thiourea
• CAS NO: 2209-25-8
• Molecular Formula: C₁₆H₁₈N₄S₂
• Molecular Weight: 330.4709
• Mol File: 2209-25-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 456.3°C at 760 mmHg
• Flash Point: 229.7°C
• Density: 1.325g/cm³
• Vapor Pressure: 1.64E-08mmHg at 25°C
• Refractive Index: 1.744
• CAS DataBase Reference: 1-(p-tolyl)-3-(p-tolylcarbamothioylamino)thiourea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(p-tolyl)-3-(p-tolylcarbamothioylamino)thiourea(2209-25-8)
• EPA Substance Registry System: 1-(p-tolyl)-3-(p-tolylcarbamothioylamino)thiourea(2209-25-8)

Safety Data

• Hazardous Substances Data: 2209-25-8(Hazardous Substances Data)

Usage

Explanation

The molecular formula represents the number of atoms of each element present in a molecule of the compound.

Explanation

A thiourea derivative is a compound that contains a thiourea functional group, which includes a sulfur atom.

Explanation

It is classified as an organic compound because it contains carbon and hydrogen atoms.

Explanation

The compound is used in the production of pharmaceuticals and dyes due to its unique chemical properties.

Explanation

The compound has shown potential for biological and pharmacological activities, making it a subject of interest for research in the medical and pharmaceutical fields.

Explanation

Its properties and potential applications make it a valuable compound for various industrial and scientific purposes.

Explanation

The compound's structure includes two p-tolyl groups and a p-tolylcarbamothioylamino group, which contribute to its unique properties and potential applications.

Explanation

As a thiourea derivative, the compound contains a sulfur atom, which is a key feature of its structure and properties.

Chemical Class

Thiourea derivative

Organic Compound

Yes

Applications

Pharmaceutical and dye manufacturing

Biological and Pharmacological Activities

Potential

Industrial and Scientific Purposes

Valuable

Structure

Contains p-tolyl and p-tolylcarbamothioylamino groups

Presence of Sulfur Atom

Yes

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Downstream Products

• 17076-46-9 5-(4-methyl-anilino)-4-p-tolyl-2,4-dihydro-[1,2,4]triazole-3-thione 
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Relevant articles and documents

Synthesis and characterization of N-glucosylated dithiadiazepine derivatives through carbon-sulfur bond formation

New 4,7-bis(arylamino)-2-tetra-O-acetyl-β-d-glucopyranosylimino-1,3,5,6-dithiadiazepines were synthesized via reaction of N-tetra-O-acetyl-β-d-glucopyranosyl isocyanodichloride with 1,6-diaryl-2,5-dithio-bis-ureas without using any catalyst. Thus, the syn

Tandem regioselective synthesis of tetrazoles and related heterocycles using iodine

A one-pot, tandem process has been developed for the synthesis of a library of tetrazoles from aryl isothiocyanates. Condensation of aryl isothiocyanates with ammonia, and aryl amines (R-NH2) provided mono, 1,3-disubstituted symmetrical and unsymmetrical thioureas, which on desulfurization with molecular iodine (I2) led to formation of the corresponding heterocumulene (cyanamides or carbodiimides). The in situ generated heterocumulene on subsequent treatment with sodium azide at room temperature gave corresponding tetrazoles. The product regioselectivity for unsymmetrical 1,3-disubstituted thioureas was found to be correlated with the basicities (pKa's) of the parent amines attached to the thiourea. Aryl-sec-alkyl unsymmetrical thioureas gave thioamido guanidino products rather than the 5-aminotetrazoles produced by HgCl2 mediation of the reaction. Bis-thioureas derived from aryl isothiocyanates and hydrazine gave thiadiazoles exclusively.