22091-49-2Relevant articles and documents
Synthesis of biphenyl oxazole derivatives via Suzuki coupling and biological evaluations as nucleotide pyrophosphatase/phosphodiesterase-1 and -3 inhibitors
Ahmad, Haseen,Hassan, Abbas,Iqbal, Jamshed,Pelletier, Julie,Rahman, Fouzia,Sévigny, Jean,Saeed, Aamer,Ullah, Saif
supporting information, (2020/09/04)
Oxazole derivatives are important medicinal compounds which are inhibitors of various enzymes such as NPP1, NPP2, NPP3, tyrosine kinase, dipeptidyl-peptidase IV, cyclooxygenase-2, and protein tyrosine phosphatase. In this study, an extensive range of new
Amino propylene glycol derivatives, its preparation method and its pharmaceutical composition and use thereof
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Paragraph 0174; 0180; 0181; 0182, (2018/11/22)
The invention discloses a class of amino propanediol derivatives, a preparation method, drug compositions and uses thereof, and particularly relates to a class of new immunoloregulation agents represented by a general formula (I), a preparation method, drug compositions containing the immunoloregulation agents, and especially uses of the immunoloregulation agents as immunoloregulation drugs. The compound with characteristics of excellent treatment effect and low toxicity can be used in the fields of immunologic derangement and immunosuppression, and can further be used for treatment of hypoimmunity, organ transplant rejection and autoimmune diseases. The formula I is defined in the instruction.
PYRROLIDINE DERIVATIVES AS HISTAMINE RECEPTORS LIGANDS
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Page/Page column 37, (2010/11/08)
The present invention relates to pyrrolidine derivatives of formula (I) having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of neurological and psychiatric disorders.