22096-70-4

Basic information

• Product Name: methyl 2-[(4-chlorophenyl)sulfanyl]benzoate
• CAS NO: 22096-70-4
• Molecular Formula: C₁₄H₁₁ClO₂S
• Molecular Weight: 278.7539
• Mol File: 22096-70-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 385.3°C at 760 mmHg
• Flash Point: 186.8°C
• Density: 1.32g/cm³
• Vapor Pressure: 3.85E-06mmHg at 25°C
• Refractive Index: 1.633
• CAS DataBase Reference: methyl 2-[(4-chlorophenyl)sulfanyl]benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-[(4-chlorophenyl)sulfanyl]benzoate(22096-70-4)
• EPA Substance Registry System: methyl 2-[(4-chlorophenyl)sulfanyl]benzoate(22096-70-4)

Safety Data

• Hazardous Substances Data: 22096-70-4(Hazardous Substances Data)

Upstream product

• 6469-85-8 2-carboxyphenyl 4-chlorophenyl sulphide 
• 1023305-05-6 [1-methoxy-3-(4-chlorophenylsulfanyl)buta-1,3-dienyloxy]trimethylsilane 
• 102-52-3 malonaldehydebis(dimethylacetal) 
• 93-58-3 benzoic acid methyl ester 
• 1146-44-7 4,4'-dichlorophenyl thiosulfonate 
• 653589-95-8 2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)benzoic acid methyl ester 
• 1142-19-4 4,4'-dichlorodiphenyl disulfide 
• 118-91-2 ortho-chlorobenzoic acid 
• 610-96-8 methyl chlorobenzoate 
• 106-54-7 p-Chlorothiophenol 

Downstream Products

• 6469-85-8 2-carboxyphenyl 4-chlorophenyl sulphide 
• 86-39-5 2-Chlorothioxanthone 

Relevant articles and documents

Syntheses, biological evaluation of some novel substituted benzoic acid derivatives bearing hydrazone as linker

On the basis of rational drug design fourteen novel compounds having benzoic acid as acidic head,?hydrazone?as?linker?and?substituted?diaryl?sulfanyl/aryl-cyclohexylsulfanyl?as?a?hydrophobic?tail?were synthesized?and?characterized by physicochemical and spectrophotometric (FTIR, Mass, 1HNMR and 13CNMR) analysis. The spectral data were satisfactory with their structures. The?designed compounds were docked against peroxisome proliferated activated receptors (PPARγ) and further evaluated for in vitro PPARγ agonist activity and in vivo hypoglycemic activity in wistar strain of albino rats.?Compound 3k and 3m exhibited potent?anti-diabetic activity without ulcerogenic toxicity and minimum side effects as weight gain. Therefore these compounds would be considered as promising agents for the development of novel antidiabetic agents.

Regioselective synthesis of 2-(arylthio)benzoates by the first catalytic [3+3] cyclocondensations of 3-(arylthio)-1-(trimethylsilyloxy)-1,3-butadienes with 1,1,3,3-tetramethoxypropane

2-(Arylthio)benzoates were regioselectively prepared by the first catalytic [3+3] cyclizations of 3-(arylthio)-1-(trimethylsilyloxy)-1,3-butadienes with 1,1,3,3-tetramethoxypropane.