221045-94-9Relevant articles and documents
Simple amino silyl ether organocatalyst for asymmetric hetero Diels–Alder reaction of isatins with enones
Parasuraman, Perumalsamy,Ganesan, Divakar,Begum, Zubeda,Seki, Chigusa,Okuyama, Yuko,Kwon, Eunsang,Uwai, Koji,Tokiwa, Michio,Tokiwa, Suguru,Takeshita, Mitsuhiro,Nakano, Hiroto
supporting information, p. 454 - 464 (2021/05/21)
New two catalysts component system comprising of a primary β-amino silyl ethers as an organocatalyst and N-protected amino acids as a co-catalyst put together worked as an efficient organocatalyst system in the hetero Diels–Alder reaction of isatins with enones affording the chiral spirooxindole-tetrahydropyranones in good chemical yields and stereoselectivities (up to 94%, up to dr 78:22., up to 85% ee).
Chirality n-heterocyclic carbine precursor compound with benzoglioxaline frameworks and preparation method and application thereof
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Paragraph 0073; 0078; 0080; 0081, (2018/09/14)
The invention discloses chirality n-heterocyclic carbine precursor compound with benzoglioxaline frameworks and a preparation method and application thereof. Five steps of reaction can simply and effectively compound a series of chirality benzoglioxaline
Characterization of lassa virus cell entry inhibitors: Determination of the active enantiomer by asymmetric synthesis
Whitby, Landon R.,Lee, Andrew M.,Kunz, Stefan,Oldstone, Michael B.A.,Boger, Dale L.
scheme or table, p. 3771 - 3774 (2010/02/28)
The comparative characterization of a series of 4-acyl-1,6-dialkylpiperazin-2-ones as potent cell entry inhibitors of the hemorrhagic fever arenavirus Lassa (LASV) is disclosed. The resolution and examination of the individual enantiomers of the prototypi
