221060-74-8

Basic information

• Product Name: 2-bromo-N-(2-hydroxy-4-methylphenyl)-5-methyl-thiophene-3-carboxamide
• Synonyms: 2-bromo-N-(2-hydroxy-4-methylphenyl)-5-methyl-thiophene-3-carboxamide
• CAS NO: 221060-74-8
• Molecular Weight: 326.214
• Mol File: 221060-74-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-bromo-N-(2-hydroxy-4-methylphenyl)-5-methyl-thiophene-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-N-(2-hydroxy-4-methylphenyl)-5-methyl-thiophene-3-carboxamide(221060-74-8)
• EPA Substance Registry System: 2-bromo-N-(2-hydroxy-4-methylphenyl)-5-methyl-thiophene-3-carboxamide(221060-74-8)

Safety Data

• Hazardous Substances Data: 221060-74-8(Hazardous Substances Data)

Upstream product

• 2835-98-5 2-Hydroxy-4-methylanilin 
• 221061-14-9 2-bromo-5-methylthiophene-3-carboxylic acid 
• 88770-18-7 methyl 5-methyl-3-thiophenecarboxylate 
• 19156-50-4 5-methyl-thiophene-3-carboxylic acid 
• 29421-92-9 4-bromo-2-methylthiophene 
• 221060-79-3 2-Bromo-5-methyl-3-thiophenecarbonyl chloride 

Downstream Products

• 1426313-35-0 3-[4-(2,8-dimethylthieno[2,3-b][1,5]benzoxazepin-4-yl)piperazin-1-yl]-2,2-dimethylpropanoic acid 4-methylbenzenesulfonic acid 

Relevant articles and documents

(THIENO[2,3-b][1,5]BENZOXAZEPIN-4-YL)PIPERAZIN-1-YL COMPOUNDS AS DUAL ACTIVITY H1 INVERSE AGONISTS/5-HT2A ANTAGONISTS

A dual H1 inverse agonist/5-HT2A receptor antagonist of the formula (I), its uses, and methods for its preparation are described.

Fused thiophene compounds and medicinal use thereof

A condensed thiophene compound of the formula (I) wherein each symbol is as defined in the specification, a pharmaceutically acceptable salt thereof and hydrates thereof. The compound of the formula (I) of the present invention is useful as a novel antipsychotic agent which is effective for both positive symptoms and negative symptoms of schizophrenia, which is associated with less side effects such as extrapyramidal motor disorder and the like and which is less associated with serious side effects such as agranulocytosis and the like. In addition, this compound is also useful as a therapeutic agent of Alzheimer's disease and manic-depressive illness.