221300-34-1Relevant articles and documents
The synthesis and antiviral activity of 4-fluoro-1-β-D-ribofuranosyl- 1h-pyrazole-3-carboxamide
Storer, Richard,Ashton, Claire J.,Baxter, Anthony D.,Hann, Michael M.,Marr, Clara L. P.,Mason, Andrew M.,Mo, Chi-Leung,Myers, Peter L.,Noble, Stewart A.,Penn, Charles R.,Weir, Niall G.,Woods, Jacqueline M.,Coe, Paul L.
, p. 203 - 216 (1999)
A novel fluoropyrazole ribonucleoside has been shown to have significant antiinfluenza activity in vitro. The compound is compared and contrasted with the structurally-related compound ribavirin in attempts to identify factors having significant bearing on the mode of action of both compounds.
PYRAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION
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Page/Page column 53, (2008/06/13)
There is provided compounds of formula (I), wherein R1, R2, X1, X2 and n have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a lipoxygenase (e.g. 15-lipoxygenase) is desired and/or required, and particularly in the treatment of inflammation.