22149-59-3

Basic information

• Product Name: (17S,20R)-Pregna-5-ene-3β,11α,12β,14β,20-pentol
• Synonyms: (17S,20R)-Pregna-5-ene-3β,11α,12β,14β,20-pentol;(20R)-Pregn-5-ene-3β,11α,12β,14β,20-pentol;Drevogenin D
• CAS NO: 22149-59-3
• Molecular Formula: C21H34O5
• Molecular Weight: 366.49166
• Mol File: 22149-59-3.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (17S,20R)-Pregna-5-ene-3β,11α,12β,14β,20-pentol(CAS DataBase Reference)
• NIST Chemistry Reference: (17S,20R)-Pregna-5-ene-3β,11α,12β,14β,20-pentol(22149-59-3)
• EPA Substance Registry System: (17S,20R)-Pregna-5-ene-3β,11α,12β,14β,20-pentol(22149-59-3)

Safety Data

• Hazardous Substances Data: 22149-59-3(Hazardous Substances Data)

Usage

Description

(17S,20R)-Pregna-5-ene-3β,11α,12β,14β,20-pentol is a steroidal compound derived from pregnenolone, characterized by a five-membered ring with a double bond and multiple hydroxyl groups. As a pentol, it features five hydroxyl groups and exhibits both beta (β) and alpha (α) stereochemistry. (17S,20R)-Pregna-5-ene-3β,11α,12β,14β,20-pentol serves as a precursor to other steroid hormones and is involved in key biological processes, including the regulation of metabolism, inflammation, and immune function.

Uses

Used in Pharmaceutical Industry:
(17S,20R)-Pregna-5-ene-3β,11α,12β,14β,20-pentol is utilized as a precursor in the synthesis of various steroid hormones for pharmaceutical applications. Its role in hormone regulation makes it valuable for developing treatments related to hormonal imbalances and other conditions influenced by steroid hormones.
Used in Research Applications:
In the field of medical and biological research, (17S,20R)-Pregna-5-ene-3β,11α,12β,14β,20-pentol is employed as a research tool to study the mechanisms of steroid hormone synthesis and action. Its involvement in biological processes such as metabolism, inflammation, and immune function provides insights into the development of potential therapeutic agents targeting these pathways.
Used in Diagnostic Applications:
(17S,20R)-Pregna-5-ene-3β,11α,12β,14β,20-pentol may be used in diagnostic assays to evaluate the function of enzymes involved in steroid hormone synthesis. Its presence and levels can indicate the activity of these enzymes, which can be useful in the diagnosis and monitoring of certain endocrine disorders.

Upstream product

• 98665-65-7 Dregoside D_a1 
• 98683-83-1 Dregeoside D_p1 
• 77524-37-9 tenasogenin 

Relevant articles and documents

Polyhydroxy pregnanes from Dregea volubilis

Three new polyhydroxy pregnanes named dregealol (1), volubilogenone (2) and volubilol (3) were isolated from the flowers of Dregea volubilis, and their structures elucidated from extensive 2D NMR analysis. The structure of volubilol (3) was confirmed by X

Polyoxypregnane glycosides from the flowers of Dregea volubilis

Three novel polyoxypregnane glycosides, volubiloside A, B and C (1-3), were isolated from the flowers of Dregea volubilis Linn., and their structures were elucidated as drevogenin D-3-O-β-D-glucopyranosyl (1→4)-6-deoxy-3-O-methyl-β-D-allopyranosyl (1→4)-β-D-cymaropyranosyl (1→4)-β-D-cymaropyranoside, drevogenin D-3-O-β-D-glucopyranosyl (1→4)-6-deoxy-3-O-methyl-β-D-allopyranosyl (1→4)-β-D-cymaropyranosyl (1→4)-β-D-digitoxopyranoside and drevogenin P-3-O-β-D-glucopyranosyl (1→4)-6-deoxy-3-O-methyl-β-D-allopyranosyl (1→4)-β-D-cymaropyranosyl (1→4)-β-D-cymaropyranoside, respectively, on the basis of extensive NMR experiments, MALDI-TOF MS, and some chemical strategies.