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22162-19-2

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22162-19-2 Usage

Description

(4-nitro-1,2-phenylene)dimethanol, also known as NDPM, is a nitro-substituted diol with the chemical formula C8H9NO5. It is a yellow crystalline solid that is sparingly soluble in water and has a high melting point. NDPM is used as an intermediate in the synthesis of various products, including pigments, dyes, and pharmaceuticals.

Uses

Used in Chemical Synthesis:
NDPM is used as an intermediate in the synthesis of other chemicals and materials. Its versatility as a chemical building block makes it valuable in the production of a wide range of products.
Used in Pharmaceutical Industry:
NDPM is used in the manufacture of pharmaceuticals due to its potential as a chemical intermediate for the development of new drugs and therapeutic agents.
Used in Pigment and Dye Industry:
NDPM is utilized in the production of pigments and dyes, where its chemical properties contribute to the creation of vibrant colors and stable formulations.
It is important to handle NDPM with care due to its potential health and environmental hazards, ensuring proper safety measures are in place during its use and disposal.

Check Digit Verification of cas no

The CAS Registry Mumber 22162-19-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,1,6 and 2 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 22162-19:
(7*2)+(6*2)+(5*1)+(4*6)+(3*2)+(2*1)+(1*9)=72
72 % 10 = 2
So 22162-19-2 is a valid CAS Registry Number.

22162-19-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name [2-(hydroxymethyl)-4-nitrophenyl]methanol

1.2 Other means of identification

Product number -
Other names 4-nitro-1,2-phenylenedimethanol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:22162-19-2 SDS

22162-19-2Downstream Products

22162-19-2Relevant articles and documents

The discovery of highly potent CGRP receptor antagonists

Stump, Craig A.,Bell, Ian M.,Bednar, Rodney A.,Bruno, Joseph G.,Fay, John F.,Gallicchio, Steven N.,Johnston, Victor K.,Moore, Eric L.,Mosser, Scott D.,Quigley, Amy G.,Salvatore, Christopher A.,Theberge, Cory R.,Blair Zartman,Zhang, Xu-Fang,Kane, Stefanie A.,Graham, Samuel L.,Vacca, Joseph P.,Williams, Theresa M.

, p. 214 - 217 (2009)

Rational modification of a previously identified spirohydantoin lead structure has identified a series of potent spiroazaoxindole CGRP receptor antagonists. The azaoxindole was found to be a general replacement for the hydantoin that consistently improved

HETEROCYCLIC SPIRO-COMPOUNDS AS AM2 RECEPTOR INHIBITORS

-

Page/Page column 112; 116-118, (2020/06/05)

Disclosed are compounds of the formula (I) and pharmaceutically acceptable salts thereof: wherein HET, R1, R2, R3, R4, R5, L, L1, X1, X2, X3 and q are as defined herein. The compounds are inhibitors of adrenomedullin receptor subtype 2 (AM2). Also disclosed are the compounds for use in the treatment of diseases modulated AM2, including proliferative diseases such as cancer; pharmaceutical compositions comprising the compounds; methods for preparing the compounds; and intermediates useful in the preparation of the compounds.

FlICk (fluorescent isoindole crosslinking) for peptide stapling

Todorovic, Mihajlo,Perrin, David M.

, p. 313 - 332 (2020/05/18)

The rigidification of peptide secondary structure via stapling is an important and enduring goal in the development of functional peptides for biochemical and pharmaceutical applications. In addition, the incorporation of fluorophores and chromophores has

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