22185-91-7

Basic information

• Product Name: 2-(2-bromo-4,5-dimethoxyphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide
• CAS NO: 22185-91-7
• Molecular Formula: C₂₀H₂₄BrNO₅
• Molecular Weight: 438.3123
• Mol File: 22185-91-7.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 592.3°C at 760 mmHg
• Flash Point: 312°C
• Density: 1.311g/cm³
• Vapor Pressure: 5.31E-14mmHg at 25°C
• Refractive Index: 1.557
• CAS DataBase Reference: 2-(2-bromo-4,5-dimethoxyphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-bromo-4,5-dimethoxyphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide(22185-91-7)
• EPA Substance Registry System: 2-(2-bromo-4,5-dimethoxyphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide(22185-91-7)

Safety Data

• Hazardous Substances Data: 22185-91-7(Hazardous Substances Data)

Usage

General Description

2-(2-bromo-4,5-dimethoxyphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide is a chemical compound with a complex molecular structure. It contains two main functional groups, including an amide and an acetamide, along with two aromatic rings with various methoxy groups attached to them. The presence of the bromine atom and the two methoxy groups in the molecular structure adds to its chemical diversity. 2-(2-bromo-4,5-dimethoxyphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide may have potential applications in medicinal chemistry, drug development, or organic synthesis due to its unique structure and functional groups. Further research and testing may be required to fully understand its properties and potential uses.

Upstream product

• 4697-57-8 methyl 2-(2-bromo-4,5-dimethoxyphenyl)acetate 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 4697-62-5 6-bromohomoveratric acid 
• 6831-57-8 2-bromo-4,5-dimethoxyphenylacetic acid chloride 
• 93-40-3 (3,4-Dimethoxyphenyl)acetic acid 
• 93-17-4 3,4-dimethoxyphenylacetonitrile 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 4230-93-7 3,4-dimethoxynitrostyrene 

Downstream Products

• 41823-67-0 1-(2'-bromo-4',5'-dimethoxybenzyl)-6,7-dimethoxy-3,4-dihydroisoquinoline 
• 59444-59-6 (+/-)-1-(2-bromo-4,5-dimethoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 
• 81165-40-4 3-[1-(2-Bromo-4,5-dimethoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-propionic acid 2-{3-[1-(2-bromo-4,5-dimethoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-propionyloxy}-ethyl ester; compound with oxalic acid 
• 64229-12-5 C₅₀H₆₄Br₂N₂O₁₂⁽²⁺⁾*2CH₃O₃S^(1-) 
• 60372-14-7 1-(2-Bromo-4,5-dimethoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline; hydrochloride 
• 475-81-0 glaucine 

Relevant articles and documents

Enantioselective synthesis and anti-parasitic properties of aporphine natural products

Chagas disease and visceral leishmaniasis are neglected protozoan diseases with significant impact in developing countries. Due to the limited number and toxicity of current therapies, new drug leads are urgently needed. In this work, four aporphine natural products were synthesized using an enantioselective, modular and convergent strategy, comprising eight steps in the longest linear sequence; key steps included Bischler-Napieralski cyclization/Noyori asymmetric reduction to construct the tetrahydroisoquinolines, and palladium-catalyzed arylation to close the C ring. Norglaucine, nordicentrine and dicentrine showed promising bioactivity against T. cruzi and L. infantum, suggesting potential for further development of these scaffolds as antiparasitic agents.

Discovery of Aporphine Analogues as Potential Antiplatelet and Antioxidant Agents: Design, Synthesis, Structure–Activity Relationships, Biological Evaluations, and in silico Molecular Docking Studies

To explore the potential of aporphine alkaloids, a novel series of functionalized aporphine analogues with alkoxy (OCH3, OC2H5, OC3H7) functional groups at C1/C2 of ring A and an acyl (COCH3/sub

Synthesis and antitumor activity of methoxy-indolo[1,2-a]isoquinolines

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