221907-28-4Relevant articles and documents
Synthesis and C-alkylation of C-protected β-enamino acid derivatives from oxa- thia- and imidazolines
Fustero, Santos,Diaz, Ma. Dolores,Asensio, Amparo,Navarro, Antonio,Kong, Jiang She,Aguilar, Enrique
, p. 2695 - 2712 (2007/10/03)
Various heterocycles 3a-h can be readily metallated and condensed with a variety of organic nitriles to afford C-protected β-enamino acid derivatives 1 (or 2). Procedures for alkylation of compounds 1 to obtain 2 as well as a 'one-pot' preparation of 2 from 3 are also described.