221910-24-3

Basic information

• Product Name: Ethanone, 1-[4-(2-quinolinyl)phenyl]-
• CAS NO: 221910-24-3
• Molecular Formula: C17H13NO
• Molecular Weight: 247.296
• Mol File: 221910-24-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-[4-(2-quinolinyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[4-(2-quinolinyl)phenyl]-(221910-24-3)
• EPA Substance Registry System: Ethanone, 1-[4-(2-quinolinyl)phenyl]-(221910-24-3)

Safety Data

• Hazardous Substances Data: 221910-24-3(Hazardous Substances Data)

Upstream product

• 99-90-1 para-bromoacetophenone 
• 59-31-4 2-hydroxyquinoline 
• 149104-90-5 4-acetylphenylboronic acid 
• 612-62-4 2-Chloroquinoline 
• 412034-48-1 terephthaloyl-di-malonic acid tetraethyl ester 
• 1009-61-6 1,4-Diacetylbenzene 
• 103529-16-4 2-[(trimethylsilyl)ethynyl]aniline 
• 615-43-0 2-iodophenylamine 
• 221909-99-5 1-(4-acetylphenyl)-3-(2-aminophenyl)prop-2-yn-1-one 
• 856176-89-1 2-(4-acetyl-phenyl)-quinoline-4-carboxylic acid 
• 55857-35-7 (E)-N-(2-aminobenzylidene)-4-methylaniline 

Relevant articles and documents

Synthesis and characterization of an isopropylBippyPhos precatalyst

A review of our high throughput reaction screening data revealed that BippyPhos was frequently associated with successful outcomes in Buchwald – Hartwig amination reactions. A barrier to the wider use of this ligand, particularly among those performing sm

ONO pincer type Pd(II) complexes: Synthesis, crystal structure and catalytic activity towards C-2 arylation of quinoline scaffolds

Four new palladium(II) complexes featuring ONO pincer type hydrazone ligands were synthesized and characterized by spectroscopic and single-crystal XRD analysis. These complexes showed excellent catalytic activity towards the Suzuki-Miyaura cross coupling reaction of 2-chloroquinoline derivatives with various aryl boronic acids. The main advantages over previous methodologies include low catalyst loading, less problematic reaction media (H2O-DMF (80:20%)) and a lower reaction temperature of 60 °C for optimal performance.

PdCl2(dppf)-catalyzed in situ coupling of 2-hydroxypyridines with aryl boronic acids mediated by PyBroP and the one-pot chemo- and regioselective construction of two distinct aryl-aryl bonds

We present a PdCl2(dppf)-catalyzed synthesis of 2-arylated pyridine derivatives via the in situ coupling of 2-OH pyridines and boronic acids mediated by PyBroP. In addition, the highly chemo- and regioselective construction of two different aryl-aryl bonds via a one-pot operation has also been demonstrated by the orthogonal use of this method with the Ni-catalyzed Suzuki-Miyaura coupling of phenols.