22199-14-0 Usage
Description
1-(2,3,6-trimethoxyphenyl)propan-2-amine, also known as TMA-6, is a psychoactive drug and research chemical belonging to the amphetamine class of compounds. It is a derivative of the hallucinogenic drug 2,5-dimethoxy-4-methylamphetamine (DOM) and is recognized for its psychedelic effects. TMA-6 functions as a potent serotonin receptor agonist, binding to and activating serotonin receptors in the brain, which results in altered perception, mood, and cognition. Its chemical structure features a phenyl ring with three methoxy groups and a propylamine side chain, which are responsible for its psychoactive properties.
Uses
Used in Scientific Research:
1-(2,3,6-trimethoxyphenyl)propan-2-amine is used as a research chemical for studying the effects of psychedelic compounds on the brain. Its application is primarily focused on understanding the interactions between these compounds and the serotonin receptors, which can provide insights into the mechanisms underlying their psychoactive effects.
Used in Psychopharmacology:
In the field of psychopharmacology, 1-(2,3,6-trimethoxyphenyl)propan-2-amine is used as a tool to investigate the role of serotonin receptors in modulating mood, perception, and cognition. This research can contribute to the development of new therapeutic strategies for various psychiatric disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 22199-14-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,1,9 and 9 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 22199-14:
(7*2)+(6*2)+(5*1)+(4*9)+(3*9)+(2*1)+(1*4)=100
100 % 10 = 0
So 22199-14-0 is a valid CAS Registry Number.
22199-14-0Relevant articles and documents
Discrimination and identification of the six aromatic positional isomers of trimethoxyamphetamine (TMA) by gas chromatography-mass spectrometry (GC-MS)
Zaitsu, Kei,Katagi, Munehiro,Kamata, Hiroe,Kamata, Tooru,Shima, Noriaki,Miki, Akihiro,Iwamura, Tatsunori,Tsuchihashi, Hitoshi
, p. 528 - 534 (2008/09/20)
A reliable and accurate GC-MS method was developed that allows both mass spectrometric and chromatographic discrimination of the six aromatic positional isomers of trimethoxyamphetamine (TMA). Regardless of the trifluoroacetyl (TFA) derivatization, chromatographic separation of all the investigated isomers was achieved by using DB-5ms capillary columns (30 m x 0.32 mm i.d.), with run times less than 15 min. However, the mass spectra of the nonderivatized TMAs, except 2,4,6-trimethoxyamphetmine (TMA-6), showed insufficient difference for unambiguous discrimination. On the other hand, the mass spectra of the TFA derivatives of the six isomers exhibited fragments with significant intensity differences, which allowed the unequivocal identification of all the aromatic positional isomers investigated in the present study. This GC-MS technique in combination with TFA derivatization, therefore, is a powerful method to discriminate these isomers, especially useful to distinguish the currently controlled 3,4,5-trimethoxyamphetmine (TMA-1) and 2,4,5-trimethoxyamphetmine (TMA-2) from other uncontrolled TMAs. Copyright
