222415-94-3

Basic information

• Product Name: (R)-benzyl 1-methoxy-2-oxo-2,4,5,6-tetrahydro-1H-imidazo[4,5,1-ij]quinolin-5-yl(methyl)carbamate
• CAS NO: 222415-94-3
• Molecular Weight: 367.404
• Mol File: 222415-94-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-benzyl 1-methoxy-2-oxo-2,4,5,6-tetrahydro-1H-imidazo[4,5,1-ij]quinolin-5-yl(methyl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-benzyl 1-methoxy-2-oxo-2,4,5,6-tetrahydro-1H-imidazo[4,5,1-ij]quinolin-5-yl(methyl)carbamate(222415-94-3)
• EPA Substance Registry System: (R)-benzyl 1-methoxy-2-oxo-2,4,5,6-tetrahydro-1H-imidazo[4,5,1-ij]quinolin-5-yl(methyl)carbamate(222415-94-3)

Safety Data

• Hazardous Substances Data: 222415-94-3(Hazardous Substances Data)

Upstream product

• 166742-97-8 (R)-3-Methylamino-1,2,3,4-tetrahydroquinoline maleate 
• 166742-98-9 (R)-methyl-(1,2,3,4-tetrahydro-3-quinolinyl)carbamic acid, phenylmethyl ester 
• 75315-63-8 N-(benzyloxycarbonyl)succinimide 
• 166742-99-0 ((R)-1-Methoxycarbamoyl-1,2,3,4-tetrahydro-quinolin-3-yl)-methyl-carbamic acid benzyl ester 

Downstream Products

• 179386-43-7 (R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]-quinolin-2(1H)-one 

Relevant articles and documents

Synthesis of the Selective D2 Receptor Agonist PNU-95666E from D-Phenylalanine Using a Sequential Oxidative Cyclization Strategy

Compound 1 (PNU-95666E) is a selective and high-affinity agonist at the dopamine D2 receptor subtype and is of interest as a potential agent for the treatment of Parkinson's disease. Requiring a synthetic route amenable to scale-up, a synthesis