22260-71-5

Basic information

• Product Name: 5-Oxazolol, 2-phenyl-4-(4-pyridinyl)-
• CAS NO: 22260-71-5
• Molecular Formula: C14H10N2O2
• Molecular Weight: 238.246
• Mol File: 22260-71-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-Oxazolol, 2-phenyl-4-(4-pyridinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Oxazolol, 2-phenyl-4-(4-pyridinyl)-(22260-71-5)
• EPA Substance Registry System: 5-Oxazolol, 2-phenyl-4-(4-pyridinyl)-(22260-71-5)

Safety Data

• Hazardous Substances Data: 22260-71-5(Hazardous Substances Data)

Upstream product

• 22260-72-6 4-(1-Acetyl-4(1H)-pyridylidene)-2-phenyl-2-oxazolin-5-one 
• 22260-80-6 4-(5-oxo-2-phenyl-4,5-dihydro-oxazol-4-yl)-4H-pyridine-1-carboxylic acid methyl ester 
• 21944-27-4 5-methoxycarbonyloxy-2-phenyl-oxazole 
• 110-86-1 pyridine 
• 22260-70-4 4-(5-oxo-2-phenyl-oxazol-4-ylidene)-4H-pyridine-1-carboxylic acid methyl ester 

Downstream Products

• 22260-72-6 4-(1-Acetyl-4(1H)-pyridylidene)-2-phenyl-2-oxazolin-5-one 
• 3731-53-1 4-(aminomethyl)pyridine 
• 3820-26-6 N-benzoyl-4-(aminomethyl)pyridine 
• 65-85-0 benzoic acid 

Relevant articles and documents

Identification of a Chromogen in the Assay of Hippuric Acid with Acetic Anhydride, Pyridine, and 4-(Dimethylamino)benzaldehyde

A yellow chromogen, formed in the assay system for hippuric acid which consists of acetic anhydride, pyridine, and 4-(dimethylamino)benzaldehyde, was isolated, and the structure was determined to be 4-(1-acetyl-4(1H)-pyridylidene)-2-phenyl-2-oxazolin-5-one.The structure was confirmed by the chemical conversion to known compounds as well as by NMR spectra.The conversion was accomplished by hydrolysis of the chromogen to 4-((benzoylamino)methyl)pyridine, 4-(aminomethyl)pyridine, and benzoic acid via 5-hydroxy-2-phenyl-4-(4-pyridyl)oxazole. 4-(Dimethylamino)benzaldehyde included in the assay system increased the production of the chromogen.The formation mechanism of the chromogen via an intermediate susceptible to oxidation was proposed.