222622-96-0Relevant articles and documents
Regioselective synthesis of a potent Src kinase inhibitor: 4-(2,4-Dichloro-5-methoxyphenylamino)-7-methoxy-8-(2-morpholin-4-ylethoxy) benzo[g]quinoline-3-carbonitrile
Berger, Dan M.,Birnberg, Gary,DeMorin, Frenel,Dutia, Minu,Powell, Dennis,Wang, Yanong D.
, p. 1712 - 1716 (2007/10/03)
The regioselective synthesis of compound 3, a potent Src kinase inhibitor is described. A key step in this synthesis is the regioselective thermal rearrangement of a substituted benzocyclobutene to provide a 2,3,6,7-tetrasubstituted naphthalene. An effici
Total syntheses of plagiochins A and D, macrocyclic bis(bibenzyls), by Pd(0) catalyzed intramolecular Stille-Kelly reaction
Fukuyama, Yoshiyasu,Yaso, Hideyuki,Mori, Takashi,Takahashi, Hironobu,Minami, Hiroyuki,Kodama, Mitsuaki
, p. 259 - 274 (2007/10/03)
Total syntheses of plagiochins A (1) and D (4), the former of which exhibits a significant neurotrophic activity, have been accomplished. The key 16-membered ring closure in 4 has been achieved directly from the dibromoperrottetin derivative (7) by Pd(0)