22287-32-7

Basic information

• Product Name: bicyclo[1.1.1]pentan-1-ylmethanol
• Synonyms: bicyclo[1.1.1]pentan-1-ylmethanol;(Bicyclo[1.1.1]pent-1-yl)methanol
• CAS NO: 22287-32-7
• Molecular Formula: C₆H₁₀O
• Molecular Weight: 98.15
• Mol File: 22287-32-7.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: bicyclo[1.1.1]pentan-1-ylmethanol(CAS DataBase Reference)
• NIST Chemistry Reference: bicyclo[1.1.1]pentan-1-ylmethanol(22287-32-7)
• EPA Substance Registry System: bicyclo[1.1.1]pentan-1-ylmethanol(22287-32-7)

Safety Data

• Hazardous Substances Data: 22287-32-7(Hazardous Substances Data)

Usage

General Description

Bicyclo[1.1.1]pentan-1-ylmethanol is a chemical compound with the molecular formula C8H14O. It is a bicyclic alcohol derived from bicyclo[1.1.1]pentane, which is a highly strained and unique carbon framework. Bicyclo[1.1.1]pentan-1-ylmethanol has potential applications in organic synthesis and as a building block for the preparation of various organic compounds. Its structure and reactivity make it an interesting target for chemical research, and it may have potential uses in the pharmaceutical and agrochemical industries. Further study is needed to fully understand the properties and potential applications of bicyclo[1.1.1]pentan-1-ylmethanol.

Upstream product

• 35634-10-7 [1.1.1]propellane 
• 117633-03-1 1-bicyclo<1.1.1>pentanecarboxaldehyde 
• 10555-43-8 1-Brom-3-brommethyl-cyclobutan 
• 22287-28-1 bicyclo[1.1.1]pentane-1-carboxylic acid 
• 79-37-8 oxalyl dichloride 
• 311-75-1 bicyclo[1.1.1]pentane 

Downstream Products

• 161043-38-5 1-Bromomethylbicyclo<1.1.1>pentane 

Relevant articles and documents

Substituted Pyrrolidines and Methods of Use

The invention discloses compounds of Formula (I) wherein R1, R2, R2A, R3, R3A, R4, R4A, and R5 are as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the invention.

6,7-DIHYDRO-5H-PYRROLO[3,4-B]PYRIDIN-5-ONE ALLOSTERIC MODULATORS OF THE M4 MUSCARINIC ACETYLCHOLINE RECEPTOR

The present invention is directed to 6,7-dihydro-5H-pyrrolo[3,4-b]pyridine-5-one compounds which are allosteric modulators of the M4 muscarinic acetylcholine receptor. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which M4 muscarinic acetylcholine receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which M4 muscarinic acetylcholine receptors are involved.

PROPELLANE DERIVATES AND SYNTHESIS

Disclosed herein are compounds of the general Formula (I), and methods of synthesizing substituted bicyclo[1.1.1 jpentanes. The synthetic methods described herein use a [1.1.1]propellane, a Group VIII transition metal compound, a hydride source and a reagent that can contribute a substituent to form a substituted bicycIo[1.1.1 ]pentane, such as a compound of the general Formula (I).