22297-13-8Relevant articles and documents
Structure-activity relationship of S-benzylisothiourea derivatives to induce spherical cells in Escherichia coli
Iwai, Noritaka,Ebata, Takuma,Nagura, Hirokatsu,Kitazume, Tomoya,Nagai, Kazuo,Wachi, Masaaki
, p. 2265 - 2269 (2004)
We have previously reported that a novel S-benzylisothiourea derivative, S-(3,4-dichlorobenzyl)isothiourea, tentatively named A22, induced spherical cells in Escherichia coli. To elucidate the structural element(s) required for inducing these spherical ce
Antibiotics targeting MreB
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Page/Page column 11; 27, (2008/06/13)
The identification of MreB as essential for bacterial chromosome segregation provides a new target for antibiotic action. The MreB function is useful in the development of screening assays for new antibiotics, which may use, for example, genetic mutants i