22333-59-1Relevant articles and documents
Effect of 9-hydroxy-α-and 7-hydroxy-β-pyran naphthoquinones on trypanosoma cruzi and structure-Activity relationship studies
Da Rocha, David R.,De Souza, Alessandra M.T.,De Souza, Ana Carolina G.,Castro, Helena C.,Rodrigues, Carlos R.,Menna-Barreto, Rubem F.S.,De Castro, Solange L.,Ferreira, Vitor F.
, p. 564 - 570 (2014/11/08)
The available treatment for the prevention and cure of Chagas disease, caused by the protozoan Trypanosoma cruzi, is still unsatisfactory. Thus, there is an urgent need to develop new drugs. In the last few years, our research group has focused on finding
Synthesis of new 9-hydroxy-α- and 7-hydroxy-β-pyran naphthoquinones and cytotoxicity against cancer cell lines
Da Rocha, David R.,De Souza, Ana C. G.,Resende, Jackson A. L. C.,Santos, Wilson C.,Dos Santos, Evelyne A.,Pessoa, Claudia,De Moraes, Manoel O.,Costa-Lotufo, Leticia V.,Montenegro, Raquel C.,Ferreira, Vitor F.
, p. 4315 - 4322 (2011/07/08)
A synthetic method to obtain α- and β-pyran naphthoquinones 10 and 11 with a hydroxyl substituent on the aromatic ring was developed. Two series of α- and β-pyran naphthoquinones were obtained from the 8-hydroxy-lawsone, and their anticancer properties we
