22359-67-7

Basic information

• Product Name: 3-(4-METHOXYPHENYL)-1-(2-NAPHTHYL)-PROP-2-EN-1-ONE
• Synonyms: 3-(4-METHOXYPHENYL)-1-(2-NAPHTHYL)-PROP-2-EN-1-ONE;(E)-3-(4-METHOXYPHENYL)-1-(NAPHTHALEN-3-YL)PROP-2-EN-1-ONE;(2E)-3-(4-Methoxyphenyl)-1-(2-naphthyl)-2-propen-1-one;1-(2-Naphthyl)-3-(4-methoxyphenyl) prop-2-en-1-one;3-(4-METHOXYPHENYL)-1-(2-NAPHTHYL)-PROP-2-EN-1-ONE 97%;3-(4-METHOXYPHENYL)-1-(NAPHTH-2-YL)PROP-2-EN-1-ONE
• CAS NO: 22359-67-7
• Molecular Formula: C₂₀H₁₆O₂
• Molecular Weight: 288.34
• Mol File: 22359-67-7.mol
• Article Data: 5

Chemical Properties

• Melting Point: 92 °C
• Boiling Point: 485.9°Cat760mmHg
• Flash Point: 220.6°C
• Appearance: /
• Density: 1.162g/cm³
• Vapor Pressure: 1.35E-09mmHg at 25°C
• Refractive Index: 1.66
• CAS DataBase Reference: 3-(4-METHOXYPHENYL)-1-(2-NAPHTHYL)-PROP-2-EN-1-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-METHOXYPHENYL)-1-(2-NAPHTHYL)-PROP-2-EN-1-ONE(22359-67-7)
• EPA Substance Registry System: 3-(4-METHOXYPHENYL)-1-(2-NAPHTHYL)-PROP-2-EN-1-ONE(22359-67-7)

Safety Data

• Safety Statements: S22:Do not inhale dust.; S24/25:Avoid contact with skin and eyes.
• Hazardous Substances Data: 22359-67-7(Hazardous Substances Data)

Usage

General Description

3-(4-Methoxyphenyl)-1-(2-naphthyl)-prop-2-en-1-one is a chemical compound with the molecular formula C20H16O2. It is a yellow solid with a melting point of 122-124°C. 3-(4-METHOXYPHENYL)-1-(2-NAPHTHYL)-PROP-2-EN-1-ONE is often used as a synthetic intermediate in the production of pharmaceuticals and other organic compounds. It is also known to exhibit biological activity, with potential applications in the fields of medicine and agriculture. However, further research is needed to fully understand its properties and potential uses.

InChI:InChI=1/C20H16O2/c1-22-19-11-6-15(7-12-19)8-13-20(21)18-10-9-16-4-2-3-5-17(16)14-18/h2-14H,1H3/b13-8+

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 93-08-3 methyl 2-naphthyl ketone 
• 75-05-8 acetonitrile 
• 7228-47-9 2-(2-naphthyl)ethanol 

Downstream Products

• 113341-19-8 3-(4-Methoxy-phenyl)-5-naphthalen-2-yl-2-naphthalen-1-yl-5-oxo-pentanenitrile 
• 113341-20-1 2-(2,6-Dichloro-phenyl)-3-(4-methoxy-phenyl)-5-naphthalen-2-yl-5-oxo-pentanenitrile 
• 127612-49-1 4-carboethoxy-4-cyano-3,5-di(4-methoxyphenyl)-2-(2-naphthyl)cyclohexanol 
• 127394-78-9 2-Methoxy-4-(4-methoxy-phenyl)-6-naphthalen-2-yl-nicotinonitrile 
• 127394-70-1 2-ethoxy-4-(4-methoxyphenyl)-6-(2-naphthyl)-pyridine-3-carbonitrile 
• 113341-21-2 2-(4-Chloro-phenyl)-3-(4-methoxy-phenyl)-5-naphthalen-2-yl-5-oxo-pentanenitrile 
• 194469-46-0 2-(4-Methoxy-phenyl)-4-naphthalen-2-yl-2,3-dihydro-benzo[b][1,4]thiazepine 
• 102875-85-4 5-(4-methyoxyphenyl)-3-(2-naphthyl)-1-phenyl-2-pyrazoline 
• 194469-52-8 2-(4-Methoxy-phenyl)-4-naphthalen-2-yl-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepine 
• 194469-58-4 5-Bromo-1-[2-(4-methoxy-phenyl)-4-naphthalen-2-yl-3,4-dihydro-2H-benzo[b][1,4]thiazepin-5-yl]-pentan-1-one 
• 1402658-60-9 5-bromo-3-{2-[5-(4-methoxyphenyl)-3-naphthalen-2-yl-4,5-dihydropyrazol-1-yl]-4-oxo-4,5-dihydro-1,3-thiazol-5-ylidene}-2,3-dihydro-1H-indol-2-one 
• 1402658-84-7 3-[5-(4-methoxyphenyl)-3-naphthalen-2-ylpyrazol-1-yl]-2,3-dihydro-1H-indol-2-one 
• 1402658-85-8 5-Chloro-3-[5-(4-methoxyphenyl)-3-naphthalen-2-yl-pyrazol-1-yl]-2,3-dihydro-1H-indol-2-one 
• 114346-60-0 C₂₀H₁₈N₂O 

Relevant articles and documents

Synthesis, Biological Activity and Action Mechanism Study of Novel Chalcone Derivatives Containing Malonate

A series of novel chalcone malonate derivatives were synthesized and their antibacterial and antiviral activities were evaluated. All target compounds were characterized by spectral data. The results of antimicrobial bioassay showed that one compound (die

Effect of ring A and ring B substitution on the cytotoxic potential of pyrazole tethered chalcones

Chalcone is an aromatic ketone that forms the central core for a variety of important biological compounds, which are collectively known as chalcones. The cytotoxic potential of chalcones which consists of C6-C 3-C6 units gets enhanced by the incorporation of pyrazole ring as proved by our earlier studies. Thus in the present work, pyrazoles of chalcones with ring A substituted by furan, naphthalene and variety of substituted phenyl rings has been prepared and evaluated for in vitro cytotoxic activity against PC-3, OVCAR, IMR-32, HEP-2 human cancer cell lines. Springer Science+Business Media, LLC 2011.

Microwave-assisted synthesis of some 3,5-arylated 2-pyrazolines

Condensation of 2-acetylnaphthalene with benzaldehydes under microwave irradiation affords chalcones which undergo facile and clean cyclizations with hydrazines RNHNH2 (R= H, Ph, Ac) to afford 3,5-arylated 2-pyrazolines in quantitative yields,