223674-40-6

Basic information

• Product Name: L-Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanyl-
• CAS NO: 223674-40-6
• Molecular Formula: C29H30N2O5
• Molecular Weight: 486.568
• Mol File: 223674-40-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: L-Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanyl-(CAS DataBase Reference)
• NIST Chemistry Reference: L-Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanyl-(223674-40-6)
• EPA Substance Registry System: L-Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanyl-(223674-40-6)

Safety Data

• Hazardous Substances Data: 223674-40-6(Hazardous Substances Data)

Upstream product

• 17498-50-9 L-valine hydrochloride 
• 86123-10-6 Fmoc-D-Phe-OH 
• 72-18-4 L-valine 
• 84890-98-2 Fmoc-Phe-O-COO-isoBu 
• 35661-40-6 N-Fmoc L-Phe 
• 103321-57-9 2S-flouren-9-ylmethoxycarbonylamino-3-phenylpropionyl chloride 
• 6306-52-1 L-valine methylester hydrochloride 
• 827018-98-4 Fmoc-Phe-Val-OMe 

Relevant articles and documents

Site-selective C(sp3)-H functionalization of di-, tri-, and tetrapeptides at the N-terminus

Although the syntheses of novel and diverse peptides rely mainly on traditional coupling using unnatural amino acids, postsynthetic modification of peptides could provide a complementary method for the preparation of nonproteinogenic peptides. Site select

Convenient peptide synthesis without protection of C-Terminals

Condensation of carboxylic acids 1 and 5 with unprotected α-amino acids 2 via activation by ethyl chloroformate and triethylamine proceeded effectively to afford the corresponding amides in 5099% yields. Tripeptide 7c was obtained in 42% yield from the dipeptide 6c in a similar manner.