223742-81-2Relevant articles and documents
Design and Synthesis of 4-Azaindoles as Inhibitors of p38 MAP Kinase
Trejo, Alejandra,Arzeno, Humberto,Browner, Michelle,Chanda, Sushmita,Cheng, Soan,Comer, Daniel D.,Dalrymple, Stacie A.,Dunten, Pete,Lafargue, JoAnn,Lovejoy, Brett,Freire-Moar, Jose,Lim, Julie,McIntosh, Joel,Miller, Jennifer,Papp, Eva,Reuter, Deborah,Roberts, Rick,Sanpablo, Florentino,Saunders, John,Song, Kyung,Villasenor, Armando,Warren, Stephen D.,Welch, Mary,Weller, Paul,Whiteley, Phyllis E.,Zeng, Lu,Goldstein, David M.
, p. 4702 - 4713 (2003)
Inhibition of the biosynthesis of proinflammatory cytokines such as tumor necrosis factor and interleukin-1 via p38 has been an approach toward the development of a disease modifying agent for the treatment of chronic inflammation and autoimmune diseases.