223801-43-2Relevant articles and documents
Medicinal uses of phenylaikanols and derivatives
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, (2008/06/13)
A compound of formula (I), a pharmaceutically acceptable derivative thereof, wherein Ph is a phenyl radical R1is H, OH, OC1-4alkyl, NO2; R2is OH, OC1-4alkyl, OC═OC1-4alkyl or OC═OPh where the Ph can be optionally substituted by halogen, C1-3alkyl or NO2; R1and R2along with the two carbon atoms of the phenyl ring to which they are attached can combine to form a 5 or 6 membered heterocyclic ring comprising 1 or 2 heteroatoms selected from O, S or N; R3is an optionally substituted hydroycarby radical; R4is H, CH3, OH or ═O; when R4is ═O, then the carbon to which R4is attached is not bonded to H; W is C(═O)—CH2, CH═CH—, CH2CO, CH(OH)—CH2, C(CH3)(OH)CH2, CH2CH(OH), CH2C(CH3)OH, CO, CHOH, C(CH3)(OH), CH2, CH2CH2; X is —CH—OH, C(CH3)OH, CH2, CH(CH3) or —C═O; Y is —CH—OH, C(CH3)OH, CH2, CH(CH3) or —C═O; provided that one of W, X or Y has an OH group.
