22396-14-1

Basic information

• Product Name: Cyclopropaneacetic acid, a-acetyl-, ethyl ester
• Synonyms: ethyl 2-cyclopropyl-3-oxobutanoate;2-Cyclopropyl-3-oxo-butyric acid ethyl ester
• CAS NO: 22396-14-1
• Molecular Formula: C9H14O3
• Molecular Weight: 170.20600
• Mol File: 22396-14-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Cyclopropaneacetic acid, a-acetyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopropaneacetic acid, a-acetyl-, ethyl ester(22396-14-1)
• EPA Substance Registry System: Cyclopropaneacetic acid, a-acetyl-, ethyl ester(22396-14-1)

Safety Data

• Hazardous Substances Data: 22396-14-1(Hazardous Substances Data)

Upstream product

• 6542-60-5 2-cyclopropylacetonitrile 
• 918907-28-5 2-cyclopropyl-3-oxobutyronitrile 
• 64-17-5 ethanol 

Downstream Products

• 854133-15-6 2-cyclopropyl-N-[2-(3-fluoro-phenyl)-ethyl]-2-(2-methyl-[1,3]dioxolan-2-yl)-acetamide 
• 854133-26-9 2-cyclopropyl-N-[2-(3-fluoro-phenyl)-ethyl]-3-oxo-butyramide 

Relevant articles and documents

New series of antiprion compounds: Pyrazolone derivatives have the potent activity of inhibiting protease-resistant prion protein accumulation

To find effective antiprion compounds, we synthesized and evaluated various pyrazolone derivatives. Seven of 19 compounds showed inhibition of PrP-res accumulation and the remarkably active compound 13 showed an IC50 value of 3 nM in both ScN2a and F3 cell lines. Findings from studies on physicochemical and biochemical properties suggest that the action mechanism of these compounds does not correlate with any antioxidant activities, any of hydroxyl radical scavenging activities, or any SOD-like activities.