22426-27-3

Basic information

• Product Name: 2-cyano-3-methylbutanoic acid
• CAS NO: 22426-27-3
• Molecular Formula: C₆H₉NO₂
• Molecular Weight: 127.1412
• Mol File: 22426-27-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 259.6°C at 760 mmHg
• Flash Point: 110.8°C
• Density: 1.092g/cm³
• Vapor Pressure: 0.00385mmHg at 25°C
• Refractive Index: 1.449
• CAS DataBase Reference: 2-cyano-3-methylbutanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-cyano-3-methylbutanoic acid(22426-27-3)
• EPA Substance Registry System: 2-cyano-3-methylbutanoic acid(22426-27-3)

Safety Data

• Hazardous Substances Data: 22426-27-3(Hazardous Substances Data)

Upstream product

• 3213-49-8 ethyl 2-isopropylcyanoacetate 
• 693-03-8 n-butyl magnesium bromide 
• 60-29-7 diethyl ether 
• 759-21-7 2-cyano-3-methylbut-2-enoic acid 
• 71-43-2 benzene 

Downstream Products

• 2813-69-6 3-methyl-2-methylenebutanenitrile 
• 67498-02-6 meso-2,3-Diisopropyl-bernsteinsaeure-nitril 
• 67498-02-6 rac.-2.3-Diisopropyl-bernsteinsaeure-dinitril 
• 143100-08-7 (1S,2R,4R)-10-dicyclohexylsulfamoylisobornyl (S)-3-phenyl-2-isopropyl-2-cyanopropanoate 
• 143100-09-8 (1S,2R,4R)-10-dicyclohexylsulfamoylisobornyl (R)-3-phenyl-2-isopropyl-2-cyanopropanoate 
• 154520-37-3 (3R)-3-Isopropyl-3-propyl-2-azetidinone 
• 154520-26-0 (2R)-(1S,2R,4R)-10-(Dicyclohexylsulfamoyl)isobornyl 2-(aminomethyl)-2,3-dimethylbutanoate 
• 154520-27-1 (2R)-(1S,2R,4R)-10-(Dicyclohexylsulfamoyl)isobornyl 2-(aminomethyl)-2-isopropylpentanoate 
• 188183-29-1 (2RS)-(1S,2R,4R)-10-(Dicyclohexylsulfamoyl)isobornyl 3-methyl-2-cyanobutanoate 
• 154520-28-2 (2R)-(1S,2R,4R)-10-(Dicyclohexylsulfamoyl)isobornyl 2-(aminomethyl)-2-benzyl-3-methylbutanoate 
• 154520-16-8 (2R)-(1S,2R,4R)-10-(Dicyclohexylsulfamoyl)isobornyl 2-cyano-2,3-dimethylbutanoate 
• 154520-17-9 (2R)-(1S,2R,4R)-10-(Dicyclohexylsulfamoyl)isobornyl 2-cyano-2-isopropyl-4-pentenoate 
• 51789-55-0 (1S,2S,4S)-2-Isopropyl-bicyclo[2.2.1]hept-5-ene-2-carbonitrile 
• 51789-55-0 (1R,2S,4R)-2-Isopropyl-bicyclo[2.2.1]hept-5-ene-2-carbonitrile 

Relevant articles and documents

Method for producing 5-isopropyluracil

A method for producing 5-isopropyluracil at a high yield in a short time, wherein N-(2-cyano-3-methylbutanoyl)urea is reduced in a 10-15% aqueous sulfuric acid solution in the presence of palladium carbon at 30-45° C., heated for ring closure reaction and added to a 50-70% aqueous sulfuric acid solution to give 5-isopropyluracil having a high purity.