22426-28-4Relevant articles and documents
Mechanistic Change from (ElcB)R to (ElcB)i Brought about by a Sterically Bulky Substituent in Ester Hydrolysis
Inoue, Massachi,Bruice, Thomas C.
, p. 959 - 963 (1986)
The anticipated pH dependence of log krate for ElcB ester hydrolysis reactions is discussed.Rate constants for carbon acid ionization and reprotonation with a series of α-cyano esters have been determined over a limited pH range.The pH dependen