22433-92-7

Basic information

• Product Name: 1,3-Benzenedicarbonitrile, 4-methoxy-
• Synonyms: 2,4-Dicyanophenylmethylester;2,4-Dicyano-anisol;2,4-dicyanoanisole;4-Methoxy-isophthalonitrile;4-methoxyisophthalonitrile;2,4-Dicyanoanisol
• CAS NO: 22433-92-7
• Molecular Formula: C9H6N2O
• Molecular Weight: 158.159
• Mol File: 22433-92-7.mol
• Article Data: 4

Chemical Properties

• Melting Point: 204 - 205 °C (diethyl ether)
• CAS DataBase Reference: 1,3-Benzenedicarbonitrile, 4-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Benzenedicarbonitrile, 4-methoxy-(22433-92-7)
• EPA Substance Registry System: 1,3-Benzenedicarbonitrile, 4-methoxy-(22433-92-7)

Safety Data

• Hazardous Substances Data: 22433-92-7(Hazardous Substances Data)

Upstream product

• 22433-89-2 4-bromobenzene-1,3-dicarbonitrile 
• 865-33-8 potassium methanolate 
• 2024-83-1 veratronitrile 
• 67-56-1 methanol 
• 151-50-8 potassium cyanide 
• 619-72-7 4-nitrobenzonitrile 
• 623-12-1 4-chloromethoxybenzene 
• 100-66-3 methoxybenzene 
• 6939-93-1 4-bromo-isophthalic acid 
• 22487-60-1 4-bromoisophthalic acid diamide 
• 21702-84-1 2,4-dibromoanisole 
• 544-92-3 copper(I) cyanide 
• 773837-37-9 sodium cyanide 
• 7677-24-9 trimethylsilyl cyanide 

Downstream Products

• 34133-58-9 4-hydroxy-isophthalonitrile 
• 22414-19-3 2,4-Dicyan-6-nitro-anisol 

Relevant articles and documents

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New oxabispidine compounds for the treatment of cardiac arrhythmias

There is provided compounds of formula I, wherein R1, R2, R3, R41 to R46, X, Y and Z have meanings given in the description, which compounds are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.

SUBSTITUENT EFFECTS IN AROMATIC PHOTOCHEMISTRY: UV IRRADIATION OF 3,4-DIMETHOXYBENZONITRILE AND 3,4-DIMETHOXYACETOPHENONE IN THE PRESENCE OF INORGANIC ANIONS

Ultraviolet photolysis of 3,4-dimethoxybenzonitrile (Ia) and 3,4-dimethoxyacetophenone (IIa) in the presence of the hydroxide or cyanide anions leads to nucleophilic displacement of either the para or the meta methoxy substituent.The ratio of isomeric photoproducts is dependent upon the nature of the nucleophile.Photoreactions with the OH(-) anion leads exclusively to the substitution at C-3.On the other hand, both isomers are formed when acetophenone IIa is irradiated in the presence of CN(-), with the C-3/C-4 ratio ranging from 1:2 to 1:6 in dependence on the nucleophile concentration.These difference between the OH(-) and CN(-) anion are related to the results of a fluorescence quenching study which has revealed that only the observed for the quenching of the second excited state of Ia by the cyanide anion.This indicates several distinct quenching modes, in relation to the concentration dependence of regioselectivity.The activating power of -H, -CN, -COCH3, and -NO2 substituents, as measured by relative quantum yields of disappearance for 3,4-dimethoxy-R-substituted benzenes, is 1 : 2.5 : 5 : 580 and 1 : 1.5 : 6 : 1000 in their photoreactions with OH(-) and CN(-) anions, respectively.