22457-25-6Relevant articles and documents
Synthesis method of citronellal oxime
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Paragraph 0017-0020, (2021/02/13)
The invention discloses a synthesis method of citronellal oxime. The method comprises the following steps: uniformly mixing citronellal with a hydroxylamine solution, dropwise adding alkali liquor while stirring, reacting to obtain citronellal oxime, standing for layering after the reaction is finished, washing an organic layer with saturated edible salt water, drying with anhydrous sodium sulfate, and carrying out vacuum distillation to obtain a citronellal oxime finished product. According to the invention, the synthesis is carried out at room temperature, heating is not needed, the pH valueof the reaction liquid does not need to be controlled in the reaction process, the reaction yield is high, and the product purity is good; and no organic solvent is used, water is used as a reactionmedium, and the method is mild and friendly to the environment, mild in reaction condition, few in side reaction, simple in process, easy to operate and suitable for large-scale industrial production.
Cascade Process for Direct Transformation of Aldehydes (RCHO) to Nitriles (RCN) Using Inorganic Reagents NH2OH/Na2CO3/SO2F2 in DMSO
Fang, Wan-Yin,Qin, Hua-Li
, p. 5803 - 5812 (2019/05/14)
A simple, mild, and practical process for direct conversion of aldehydes to nitriles was developed feathering a wide substrate scope and great functional group tolerability (52 examples, over 90% yield in most cases) using inorganic reagents (NH2OH/Na2CO3/SO2F2) in DMSO. This method allows for transformations of readily available, inexpensive, and abundant aldehydes to highly valuable nitriles in a pot, atom, and step-economical manner without transition metals. This protocol will serve as a robust tool for the installation of cyano-moieties to complicated molecules.
Postsynthesis-Treated Iron-Based Metal-Organic Frameworks as Selective Catalysts for the Sustainable Synthesis of Nitriles
Rapeyko, Anastasia,Climent, Maria J.,Corma, Avelino,Concepci?n, Patricia,Iborra, Sara
, p. 3270 - 3282 (2015/10/19)
The dehydration of aldoximes to the corresponding nitriles can be performed with excellent activity and selectivity by using iron trimesate as a homogeneous catalyst. Iron trimesate has been heterogenized by synthesizing metal-organic frameworks (MOFs) from iron trimesate, that is, Fe(BTC), and MIL-100 (Fe). These materials were active and selective aldoxime dehydration catalysts, and postsynthesis-treated MIL-100 (Fe) produced the desired nitriles with 100 conversion and selectivities >90 under mild reaction conditions and in short reaction times. X-ray photoelectron spectroscopy showed the presence of different Fe species in the catalyst, and in situ IR spectroscopy combined with catalytic results indicates that the catalytic activity is associated with Fe framework species. The postsynthesis-treated MIL-100 (Fe)-NH4F can be recycled several times and has an excellent reaction scope, which gives better catalytic results than other solid acid or base catalysts.