224769-58-8

Basic information

• Product Name: 2-fluoro-3-formyl-8-methylquinoline
• Synonyms: 2-fluoro-3-formyl-8-methylquinoline
• CAS NO: 224769-58-8
• Molecular Weight: 189.189
• Mol File: 224769-58-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-fluoro-3-formyl-8-methylquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-fluoro-3-formyl-8-methylquinoline(224769-58-8)
• EPA Substance Registry System: 2-fluoro-3-formyl-8-methylquinoline(224769-58-8)

Safety Data

• Hazardous Substances Data: 224769-58-8(Hazardous Substances Data)

Upstream product

• 73568-26-0 2-chloro-8-methyl-quinoline-3-carbaldehyde 

Relevant articles and documents

Fluorination of 2-chloro-3-formylquinolines using microwaves

Fluorination on 2-chloro-3-formylquinolines has been carried out in sulfolane, acetonitrile and acetamide using potassium fluoride (KF) and tetramethylammonium chloride (TMAC) under microwave irradiation as well as conventional heating. The reaction time has been brought down from hours to minutes with improved yields using microwave irradiation. The rate of fluorination of 2-chloro-3-formylquinoline is more in acetamide followed by acetonitrile.