22532-47-4

Basic information

• Product Name: p-methylphenethyl acetate
• Synonyms: p-methylphenethyl acetate;Benzeneethanol, 4-methyl-, acetate;4-methyl-benzeneethano acetate;4-Methylbenzeneethanol acetate;4-METHYLPHENETHYL ACETATE
• CAS NO: 22532-47-4
• Molecular Formula: C₁₁H₁₄O₂
• Molecular Weight: 178.22766
• EINECS: 245-056-9
• Mol File: 22532-47-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 254.5°C at 760 mmHg
• Flash Point: 109.2°C
• Appearance: /
• Density: 1.018g/cm³
• Vapor Pressure: 0.0172mmHg at 25°C
• Refractive Index: 1.502
• CAS DataBase Reference: p-methylphenethyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: p-methylphenethyl acetate(22532-47-4)
• EPA Substance Registry System: p-methylphenethyl acetate(22532-47-4)

Safety Data

• Hazardous Substances Data: 22532-47-4(Hazardous Substances Data)

Usage

General Description

p-Methylphenethyl acetate is a chemical compound with a sweet, fruity odor that is commonly used in the production of perfumes and fragrances. It is a colorless liquid that is insoluble in water but soluble in alcohol and other organic solvents. p-methylphenethyl acetate is created through the esterification of p-methylphenethyl alcohol and acetic acid, and it is often used as a flavoring agent in the food industry as well. In addition to its pleasant aroma, p-methylphenethyl acetate also has potential applications in the pharmaceutical and cosmetic industries, making it a versatile and valuable chemical compound.

InChI:InChI=1/C11H14O2/c1-9-3-5-11(6-4-9)7-8-13-10(2)12/h3-6H,7-8H2,1-2H3

Upstream product

• 6529-51-7 2-(4-methylphenyl)ethyl bromide 
• 127-08-2 potassium acetate 
• 74-85-1 ethene 
• 1600-27-7 mercury(II) diacetate 
• 108-88-3 toluene 
• 622-47-9 4-tolylacetic acid 
• 75-36-5 acetyl chloride 
• 14503-40-3 2-(4-methylphenyl)ethyl tosylate 
• 64-19-7 acetic acid 
• 67-56-1 methanol 
• 65143-37-5 2-oxo-2-(4-tolyl)ethyl acetate 
• 699-02-5 4-Methylphenethyl alcohol 
• 108-24-7 acetic anhydride 

Downstream Products

• 699-02-5 4-Methylphenethyl alcohol 
• 615570-04-2 2,5-diiodo-4-methylphenethyl alcohol 

Relevant articles and documents

Novel access to carbonyl and acetylated compounds: The role of the tetra-: N -butylammonium bromide/sodium nitrite catalyst

A novel aerobic oxidation of alcohols without the use of any oxidants was developed. An equimolar catalytic mixture of tetra-n-butylammonium bromide and sodium nitrite catalyzes the aerobic selective oxidation of benzylic alcohols under oxidant-free, base-free and metal-free conditions. The mild reaction conditions allow oxidation of a wide range of benzylic alcohols, chemo-selectively to their carbonyl compounds (68-93% isolated yields). More importantly, high selectivity among different kinds of alcohols (aromatic vs. aliphatic alcohols, primary vs. secondary alcohols as well as alcohols having neutral rings vs. electron-deficient rings) is available by this approach. The method surprisingly switched over to be an efficient acetylation approach in the case of aliphatic alcohols without the use of any transition metal, phosphorous or other toxic reagents or any need for using toxic acyl halides, sulfonyl halides, anhydrides, etc. by the use of only acetic acid as a reagent.

Substituent Effects. XVI. Acetolysis of 2-Phenylethyl Tosylates

The acetolysis rates of 2-arylethyl tosylates were determined for a series of aryl substituents.The non-linear substituent effect was reasonably accounted for on the basis of two linear LArSR relationships; one for the aryl-assisted (FkΔ) and one for the unassisted (Ks) process, respectively.A precise dissection of the apparent substituent effect into individual effects for both processes was achieved in this manner.The substituent effect on the ks process can be described as a linear function of ?0 with a small ρs of -0.19, and that on the FkΔ process in terms of the LArSR Eq., with a ρΔ=-3.87 and an rΔ=0.631.The use of ?+ for the FkΔ process failed to give any reasonable dissection.The r value for this FkΔ process is essentially identical to that for the neophyl solvolysis.The unique r value oh 0.6 is concluded to be characteristic of β-aryl-assisted ionization processes in general.