22534-71-0

Basic information

• Product Name: N-acetylbutanamide
• CAS NO: 22534-71-0
• Molecular Formula: C₆H₁₁NO₂
• Molecular Weight: 129.157
• Mol File: 22534-71-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 231.7°C at 760 mmHg
• Flash Point: 105.5°C
• Density: 0.988g/cm³
• Vapor Pressure: 0.0614mmHg at 25°C
• Refractive Index: 1.426
• CAS DataBase Reference: N-acetylbutanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-acetylbutanamide(22534-71-0)
• EPA Substance Registry System: N-acetylbutanamide(22534-71-0)

Safety Data

• Hazardous Substances Data: 22534-71-0(Hazardous Substances Data)

Upstream product

• 541-35-5 butanamide 
• 108-24-7 acetic anhydride 
• 75-36-5 acetyl chloride 
• 109-90-0 ethyl isocyanate 
• 1119-49-9 N-butylacetamide 
• 106-31-0 butanoic acid anhydride 
• 75-05-8 acetonitrile 
• 109-74-0 propyl cyanide 

Downstream Products

• 60-35-5 acetamide 
• 541-35-5 butanamide 
• 623-42-7 butanoic acid methyl ester 
• 625-77-4 N-acetylacetamide 
• 105-54-4 butanoic acid ethyl ester 
• 638-11-9 isopropyl butyrate 
• 79-20-9 acetic acid methyl ester 
• 141-78-6 ethyl acetate 

Relevant articles and documents

Ultrasound-assisted catalytic synthesis of acyclic imides in the presence of p-toluenesulfonic acid under solvent-free conditions

A rapid and convenient preparation of acyclic imides by the reaction of aliphatic and aromatic nitriles with acyclic carboxylic anhydride in the presence of catalytic amounts of p-toluenesulfonic acid under thermal or ultrasonic conditions is reported. The advantages of this procedure are moderate reaction times, good to excellent yields, and use of an inexpensive and ecofriendly catalyst. The reaction of nitriles with aliphatic anhydrides proceeds under thermal conditions, while they are accelerated by the use of ultrasound irradiation.

Efficient synthesis of symmetrical and unsymmetrical acyclic imides catalyzed by reusable 12-tungstophosphoric acid under thermal conditions and microwave irradiation

An efficient and environmentally friendly procedure has been developed for the synthesis of symmetrical and unsymmetrical acyclic imides by the reaction of nitriles with acyclic anhydrides in the presence of catalytic amounts of 12-tungstophosphoric acid (H3PW12O40) under thermal conditions and microwave irradiation. It was found that microwave improves the yields and significantly reduces the reaction times. Furthermore, the catalyst could be recovered and reused several times without decrease in its activity.

A bromine-catalysed free-radical oxidation of acetamides from primary and secondary alkylamines by H2O2

New procedures based on the oxidation by bromine-catalysed hydrogen peroxide in a two-phase system provide simple and cheap transformations of alkylamines to carbonyl derivatives (aldehydes, ketones, carboxylic acid, imides, lactams) through the corresponding acetamides.