2256-23-7Relevant articles and documents
A novel mitochondrial targeting fluorescent probe for ratiometric imaging SO2 derivatives in living cells
Wang, Xiao-Bo,Li, Hui-Jing,Chi, Zhenxing,Zeng, Xianshun,Wang, Li-Juan,Cheng, Yun-Fei,Wu, Yan-Chao
, (2019/12/30)
As an important endogenous signaling molecule, SO2 plays a key role in many physiological processes. However, excessive intake of SO2 and its derivatives lead to serious health complications of various diseases. In order to study the role of SO2 and its derivatives in the biological environment, it is of great significance to develop new and effective monitoring methods. Here, a new red emission fluorescent probe (TNPI) based on pyrazoline and hemicyanine dyes for the high selective detection of SO2 derivatives was developed. The probe TNPI showed some advantages such as long emission wavelength (640 nm), obvious color and fluorescence changes after reaction with SO2 derivatives, high selectivity and sensitivity toward SO2 derivatives (detection limit = 80 nM), and large fluorescence emission shift (160 nm) and signal ratio change (from 0.45–445, about 989 times). Intriguingly, the probe was successfully exploited for the fluorescence imaging of SO2 derivatives in the mitochondria of living cells with low cytotoxicity.
KHSO4 · H2O/SiO2-catalyzed, one-pot, solvent-free synthesis of pyrazolines, tetrahydrocarbozoles and indoles using microwave irradiation
Kapoor, Kamal K.,Ganai, Bilal A.,Kumar, Satish,Andotra, Charanjeet S.
, p. 2727 - 2735 (2007/10/03)
A new high-yielding, operationally simple, solvent-free, and mild method for preparation of pyrazolines, tetrahydrocarbazoles, and indoles has been developed using KHSO4 · H2O impregnated on SiO 2. The reactions have been probed under microwave irradiation (MWI), and ultrasonic and thermal conditions, employing different solid supports. The data revealed that KHSO4 · H2O impregnated on SiO2 under MWI provides the best yields in a shorter time under solvent-free reaction conditions. Copyright Taylor & Francis Group, LLC.