22568-64-5

Basic information

• Product Name: (±)-N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]acetamide
• Synonyms: (±)-N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]acetamide;rac Diacetolol;1-(4-AcetaMido-2-acetylphenoxy)-2-hydroxy-3-isopropylaMinopropane;DL-3'-Acetyl-4'-[2-hydroxy-3-(isopropylaMino)propoxy]acetanilide;Acebutolol EP IMpurity B;Acebutolol Impurity B HCl;N-{3-Acetyl-4-{(2RS)-2-hydroxy-3-[(1-methylethyl)amino]propoxy}phenyl}acetamide
• CAS NO: 22568-64-5
• Molecular Formula: C₁₆H₂₄N₂O₄
• Molecular Weight: 308.37276
• EINECS: 245-088-3
• Product Categories: Amines;Aromatics;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
• Mol File: 22568-64-5.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 548.8 °C at 760 mmHg
• Flash Point: 285.7 °C
• Appearance: /
• Density: 1.152 g/cm³
• Vapor Pressure: 7.08E-13mmHg at 25°C
• Refractive Index: 1.551
• Storage Temp.: Refrigerator, under inert atmosphere
• Solubility: Chloroform (Very Slightly), DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: (±)-N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: (±)-N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]acetamide(22568-64-5)
• EPA Substance Registry System: (±)-N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]acetamide(22568-64-5)

Safety Data

• Hazardous Substances Data: 22568-64-5(Hazardous Substances Data)

Usage

Description

(±)-N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]acetamide is a complex organic compound with a unique chemical structure. It is characterized by its acetamide functional group and a phenyl ring with various substituents, including an acetyl group, a hydroxyl group, and an aminopropoxy group. This molecule exhibits a range of biological activities and has potential applications in various industries due to its unique properties.

Uses

Used in Pharmaceutical Industry:
(±)-N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]acetamide is used as a pharmaceutical compound for its potential therapeutic effects. The compound's unique structure allows it to interact with specific biological targets, making it a promising candidate for the development of new drugs.
Used in Cardiovascular Applications:
In the cardiovascular field, (±)-N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]acetamide is used as a metabolite of Acebutolol (A123800), which possesses less β-adrenoceptor blocking potency but greater cardioselectivity (atrial relative to tracheal tissue). This property makes it a valuable compound for the treatment of various cardiovascular conditions, as it can selectively target specific tissues without causing unwanted side effects.
Used in Drug Synthesis:
(±)-N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]acetamide can also be used as a key intermediate in the synthesis of other pharmaceutical compounds. Its unique structure and functional groups make it a versatile building block for the development of new drugs with improved efficacy and selectivity.
Used in Research and Development:
Due to its complex structure and potential biological activities, (±)-N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]acetamide is also used in research and development for the study of various biological processes and the development of novel therapeutic strategies. Researchers can use this compound to investigate its interactions with different biological targets and explore its potential applications in various therapeutic areas.

InChI:InChI=1/C16H24N2O4/c1-10(2)17-8-14(21)9-22-16-6-5-13(18-12(4)20)7-15(16)11(3)19/h5-7,10,14,17,21H,8-9H2,1-4H3,(H,18,20)