2258-59-5

Basic information

• Product Name: 4-Pentenoic acid, 4-methyl-, methyl ester
• CAS NO: 2258-59-5
• Molecular Formula: C7H12O2
• Molecular Weight: 128.171
• Mol File: 2258-59-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-Pentenoic acid, 4-methyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Pentenoic acid, 4-methyl-, methyl ester(2258-59-5)
• EPA Substance Registry System: 4-Pentenoic acid, 4-methyl-, methyl ester(2258-59-5)

Safety Data

• Hazardous Substances Data: 2258-59-5(Hazardous Substances Data)

Upstream product

• 513-37-1 2-methylprop-1-enyl chloride 
• 18424-76-5 dimethyl malonate sodium salt 
• 13061-96-6 dihydroxy-methyl-borane 
• 194805-62-4 methyl-4-bromo-pent-4-enoate 
• 67-56-1 methanol 
• 201230-82-2 carbon monoxide 
• 78-79-5 isoprene 

Downstream Products

• 1282061-03-3 4-methyl-N-p-tolylpent-4-enamide 
• 1453416-15-3 4,5-dihydroxy-4-methyl-N-p-tolylpentanamide 
• 87433-66-7 3-(1-methylcyclopropyl)propanoic acid 
• 1001-75-8 4-methyl-4-pentenoic acid 
• 22508-64-1 4-methyl-4-penten-1-ol 

Relevant articles and documents

Regioselective palladium-catalysed coupling reactions of vinyl chlorides with carbon nucleophiles

Vinyl chlorides bearing methyl groups in the 2-position can be activated catalytically by palladium(0)-complexes of 1,4-bis(dicyclohexylphosphino)butane, the process involving vinyl-allyl isomerization via CH-activation followed by nucleophilic attack of

Asymmetric bromolactonization using amino-thiocarbamate catalyst

A novel amino-thiocarbamate-catalyzed bromolactonization of unsaturated carboxylic acids has been developed. The scope of the reaction is evidenced by 22 examples of γ-lactones with up to 99% yield and 93% ee. The protocol was applied in the enantioselective synthesis of the key intermediates of VLA-4 antagonists.