226070-43-5Relevant articles and documents
Nucleophilic Substitutions of Alcohols in High Levels of Catalytic Efficiency
Stach, Tanja,Dr?ger, Julia,Huy, Peter H.
, p. 2980 - 2983 (2018)
A practical method for the nucleophilic substitution (SN) of alcohols furnishing alkyl chlorides, bromides, and iodides under stereochemical inversion in high catalytic efficacy is introduced. The fusion of diethylcyclopropenone as a simple Lewis base organocatalyst and benzoyl chloride as a reagent allows notable turnover numbers up to 100. Moreover, the use of plain acetyl chloride as a stoichiometric promotor in an invertive SN-type transformation is demonstrated for the first time. The operationally straightforward protocol exhibits high levels of stereoselectivity and scalability and tolerates a variety of functional groups.
Highly selective acylation of alcohols and amines by an indium triiodide-catalysed transesterification process
Ranu, Brindaban C.,Dutta, Pinak,Sarkar, Arunkanti
, p. 2223 - 2225 (2007/10/03)
A very simple method has been developed for the acylation of alcohols and amines by ethyl acetate through an indium triiodide-catalysed transesterification process. Using this method acylation of a primary OH group in the presence of secondary and phenolic OH groups, and of a primary NH2 in the presence of secondary NH and primary OH have been achieved with high selectivity. The Royal Society of Chemistry 2000.
