226417-31-8

Basic information

• Product Name: Benzyl (1-methylpent-4-enyl) sulfide
• Synonyms: Benzyl (1-methylpent-4-enyl) sulfide
• CAS NO: 226417-31-8
• Molecular Weight: 206.352
• Mol File: 226417-31-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzyl (1-methylpent-4-enyl) sulfide(CAS DataBase Reference)
• NIST Chemistry Reference: Benzyl (1-methylpent-4-enyl) sulfide(226417-31-8)
• EPA Substance Registry System: Benzyl (1-methylpent-4-enyl) sulfide(226417-31-8)

Safety Data

• Hazardous Substances Data: 226417-31-8(Hazardous Substances Data)

Upstream product

• 109-49-9 5-Hexen-2-one 
• 4558-27-4 5-bromohex-1-ene 
• 100-53-8 phenylmethanethiol 
• 100-39-0 benzyl bromide 
• 204520-65-0 (2R,5R)-2,5-dimethyltetrahydrothiophene 

Downstream Products

• 14310-20-4 4-methylbibenzyl 

Relevant articles and documents

Thioether-Directed NiH-Catalyzed Remote γ-C(sp3)-H Hydroamidation of Alkenes by 1,4,2-Dioxazol-5-ones

A NiH-catalyzed thioether-directed cyclometalation strategy is developed to enable remote methylene C-H bond amidation of unactivated alkenes. Due to the preference for five-membered nickelacycle formation, the chain-walking isomerization initiated by the NiH insertion to an alkene can be terminated at the γ-methylene site remote from the alkene moiety. By employing 2,9-dibutyl-1,10-phenanthroline as the ligand and dioxazolones as the reagent, the amidation occurs at the γ-C(sp3)-H bonds to afford the amide products in up to 90% yield (>40 examples) with remarkable regioselectivity (up to 24:1 rr).