226571-61-5Relevant articles and documents
PURINE DERIVATIVES USEFUL AS HSP90 INHIBITORS
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Page/Page column 117-118, (2011/04/26)
The present application provides substituted purine derivatives and related compounds of the formulas shown. These com ounds are useful as inhibitors of HSP90, and hence in the treatment of related diseases. (Formulae) Z1-Z3, Xa-Xc, X2, X4, Y and R are as defined in the specification.
Imidiazoles having reduced side effects
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, (2008/06/13)
Methods and compounds for the treatment of conditions including pain, particularly chronic pain, glaucoma or elevated intraocular pressure with reduced cardiovascular or sedative side effects. Also included are methods of making and using such compounds.