22661-23-0

Basic information

• Product Name: N-benzyl-4-nitro-isobenzaldoxime
• Synonyms: N-benzyl-4-nitro-isobenzaldoxime
• CAS NO: 22661-23-0
• Molecular Weight: 256.261
• Mol File: 22661-23-0.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: N-benzyl-4-nitro-isobenzaldoxime(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyl-4-nitro-isobenzaldoxime(22661-23-0)
• EPA Substance Registry System: N-benzyl-4-nitro-isobenzaldoxime(22661-23-0)

Safety Data

• Hazardous Substances Data: 22661-23-0(Hazardous Substances Data)

Upstream product

• 555-16-8 4-nitrobenzaldehdye 
• 100-46-9 benzylamine 
• 29601-98-7 N-benzylhydroxylamine hydrochloride 
• 55648-93-6 N-benzyl-N-(4-nitrobenzyl)hydroxylamine 
• 22661-28-5 N-(4-nitro-benzyl)-benzaldoxime 
• 141-52-6 sodium ethanolate 
• 932-90-1 Benzaldoxime 
• 100-52-7 benzaldehyde 
• 622-30-0 N-benzyl hydroxylalmine 
• 126178-30-1 (E)-N-benzyl-1-(4-nitrophenyl)methanimine 
• 100-44-7 benzyl chloride 
• 1129-37-9 4-nitrobenzaldoxime 

Downstream Products

• 1217732-64-3 C₃₀H₂₄N₂O₃ 
• 1165676-85-6 N-benzyl-N-(1-(4-nitrophenyl)-3-phenylprop-2-yn-1-yl)hydroxylamine 
• 7501-91-9 3-[(1H-indol-3-yl)(4-nitrophenyl)methyl]-1H-indole 
• 555-16-8 4-nitrobenzaldehdye 
• 622-30-0 N-benzyl hydroxylalmine 

Relevant articles and documents

S -Tetrazine: Robust and Green Photoorganocatalyst for Aerobic Oxidation of N,N-Disubstituted Hydroxylamines to Nitrones

Efficient photocatalytic aerobic oxidative dehydrogenation reactions of N,N-disubstituted hydroxylamines to nitrones were developed with an in situ generated photocatalyst based on commercially available 3,6-dichlorotetrazine. This process affords a wide range of nitrones in high yields under mild conditions. In addition, an oxidative (3+3) cycloaddition between an oxyallyl cation precursor and a hydroxylamine was also developed.

BPh3-Catalyzed [2+3] Cycloaddition of Ph3PCCO with Aldonitrones: Access to 5-Isoxazolidinones with Exocyclic Phosphonium Ylide Moieties

A method for the generation of 5-isoxazolidinones with exocyclic phosphonium ylide functionalities via [2+3] cycloaddition of Ph3PCCO and aldonitrones has been developed and applied in the synthesis of 4-alkylidene-5-isoxazolidinones via Wittig olefination. The reaction proceeds by BPh3 catalysis under mild conditions and with a broad substrate scope. A reaction pathway involving the activation of the aldonitrone via interactions with the Lewis acid BPh3 is proposed.

Synthesis of 4-Isoxazolines through Gold(I)-Catalyzed Cyclization of Propargylic N-Hydroxylamines

New catalytic methods for the synthesis of 4-isoxazolines have been developed via catalytic intramolecular cyclizations of propargylic N-hydroxylamines. The reactions proceed rapidly in less than 1 h at room temperature in the presence of 5 mol % (PPh3)AuCl/5 mol % AgOTf or 5 mol % (PPh3)AuNTf2. This process features an efficient route to 4-isoxazolines with high yields, short reaction times, and mild reaction conditions.