226895-51-8

Basic information

• Product Name: dimethyl 2-(2-bromo-3-nitrophenyl)-1,1-ethanedicarboxylate
• Synonyms: dimethyl 2-(2-bromo-3-nitrophenyl)-1,1-ethanedicarboxylate
• CAS NO: 226895-51-8
• Molecular Weight: 346.134
• Mol File: 226895-51-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: dimethyl 2-(2-bromo-3-nitrophenyl)-1,1-ethanedicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl 2-(2-bromo-3-nitrophenyl)-1,1-ethanedicarboxylate(226895-51-8)
• EPA Substance Registry System: dimethyl 2-(2-bromo-3-nitrophenyl)-1,1-ethanedicarboxylate(226895-51-8)

Safety Data

• Hazardous Substances Data: 226895-51-8(Hazardous Substances Data)

Upstream product

• 108-59-8 malonic acid dimethyl ester 
• 82617-49-0 2-bromo-1-bromomethyl-3-nitrobenzene 
• 18424-76-5 sodiodimethylmalonate 

Downstream Products

• 226895-52-9 dimethyl 1-(2-bromo-3-nitrophenyl)pent-4-ene-2,2-dicarboxylate 

Relevant articles and documents

Synthesis of fused indoles by sequential palladium-catalyzed Heck reaction and N-heteroannulation

A route to 3,4-fused indoles via two consecutive palladium-catalyzed reactions; an intramolecular Heck reaction followed by a reductive N-heteroannulation is described. Using this route, a number of indoles have been prepared having a variety of ring sizes anchored to the 3- and 4-position of the indole nucleus. Furthermore, a number of functional groups, both carbon and heteroatom substituents can be introduced in (and on) the additional ring without any detrimental effects on the two reactions.