226903-07-7 Usage
Description
6-Hydroxy-6-defluoro Ciprofloxacin, also known as Ciprofloxacin EP Impurity F, is a hydroxy analog of Ciprofloxacin (C482500). It is an off-white to pale beige solid with unique chemical properties that differentiate it from its parent compound, Ciprofloxacin.
Uses
Used in Pharmaceutical Industry:
6-Hydroxy-6-defluoro Ciprofloxacin is used as an active pharmaceutical ingredient (API) for the development of new antibiotics. Its chemical structure provides it with distinct properties that may offer advantages over the original Ciprofloxacin, potentially leading to improved efficacy, reduced side effects, or enhanced activity against resistant bacteria.
Used in Research and Development:
In the field of scientific research, 6-Hydroxy-6-defluoro Ciprofloxacin serves as a valuable compound for studying the structure-activity relationship of fluoroquinolone antibiotics. This understanding can guide the design and synthesis of novel antibiotics with improved characteristics.
Used in Quality Control:
6-Hydroxy-6-defluoro Ciprofloxacin is utilized as a reference standard in the quality control and assurance processes of pharmaceutical manufacturing. It helps ensure the purity, potency, and consistency of Ciprofloxacin-based medications, contributing to patient safety and the overall quality of the drug products.
Used in Drug Synthesis:
As a key intermediate in the synthesis of various fluoroquinolone antibiotics, 6-Hydroxy-6-defluoro Ciprofloxacin plays a crucial role in the development of new drugs with potential applications in treating bacterial infections. Its unique chemical properties may facilitate the creation of more effective and targeted antibiotic therapies.
Used in Drug Resistance Studies:
6-Hydroxy-6-defluoro Ciprofloxacin is employed in research aimed at understanding and combating antibiotic resistance. By studying the interactions between this compound and bacterial resistance mechanisms, scientists can gain insights into the development of new strategies to overcome resistance and preserve the effectiveness of existing antibiotics.
Used in Veterinary Medicine:
In the veterinary industry, 6-Hydroxy-6-defluoro Ciprofloxacin may be used as an API for the development of antibiotics specifically tailored to treat bacterial infections in animals. This can help maintain the health of livestock and pets, as well as prevent the spread of zoonotic diseases to humans.
Check Digit Verification of cas no
The CAS Registry Mumber 226903-07-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,6,9,0 and 3 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 226903-07:
(8*2)+(7*2)+(6*6)+(5*9)+(4*0)+(3*3)+(2*0)+(1*7)=127
127 % 10 = 7
So 226903-07-7 is a valid CAS Registry Number.
226903-07-7Relevant articles and documents
Photochemistry of 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(piperazin-1-yl)quinoline-3- carboxylic acid (=ciprofloxacin) in aqueous solutions
Mella, Mariella,Fasani, Elisa,Albini, Angelo
, p. 2508 - 2519 (2007/10/03)
The 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(piperazin-1-yl)quinoline-3- carboxylic acid (=ciprofloxacin; 1) undergoes low-efficiency (φ=0.07) substitution of the 6-fluoro by an OH group on irradiation in H2O via the ππ* triplet (detected by
