227312-12-1

Basic information

• Product Name: 3-Thiophenecarboxylic acid, 5-nitro-4-[(phenylmethyl)thio]-, methyl ester
• Synonyms: methyl 4-(benzylsulfanyl)-5-nitro-3-thiophenecarboxylate
• CAS NO: 227312-12-1
• Molecular Formula: C₁₃H₁₁NO₄S₂
• Molecular Weight: 309.36074
• Mol File: 227312-12-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Thiophenecarboxylic acid, 5-nitro-4-[(phenylmethyl)thio]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Thiophenecarboxylic acid, 5-nitro-4-[(phenylmethyl)thio]-, methyl ester(227312-12-1)
• EPA Substance Registry System: 3-Thiophenecarboxylic acid, 5-nitro-4-[(phenylmethyl)thio]-, methyl ester(227312-12-1)

Safety Data

• Hazardous Substances Data: 227312-12-1(Hazardous Substances Data)

Upstream product

• 100-53-8 phenylmethanethiol 
• 227312-09-6 4-((4-methylphenyl)sulfonyl)oxy-5-nitro-3-thiophenecarboxylic acid methyl ester 
• 35717-30-7 4-bromo-5-nitro-3-thiophenecarboxylic acid methyl ester 
• 16694-17-0 4-bromo-3-thiophenecarboxylic acid 
• 101079-65-6 4-bromo-5-nitrothiophene-3-carboxylic acid 
• 67525-75-1 methyl 2,5-dihydro-4-(p-toluenesulfonato)thiophene-3-carboxylate 
• 227312-07-4 4-((4-methylphenyl)sulfonyl)oxy-3-thiophenecarboxylic acid methyl ester 

Downstream Products

• 227312-14-3 5-amino-4-(phenylmethyl)thio-3-thiophenecarboxylic acid methyl ester 
• 686271-29-4 (4-benzylsulfanyl-5-nitro-thiophen-3-yl)-methanol 
• 1002761-79-6 3-benzylsulfanyl-4-chloromethyl-2-nitro-thiophene 
• 1002761-80-9 N-tert-butyl ester-N-(4-benzylsulfanyl-5-nitro-thiophen-3-ylmethyl)-methanesulfonamide 

Relevant articles and documents

Anti-infective agents

Compounds having the formula are hepatitis C (HCV) polymerase inhibitors. Also disclosed are a composition and method for inhibiting hepatitis C (HCV) polymerase, processes for making the compounds, and synthetic intermediates employed in the processes.

An improved synthetic approach to thieno[2,3-d]-1,2,3-thiadiazole- carboxylates via diazotization of aminothiophene derivatives

The common synthetic method for the synthesis of fused 1,2,3- thiadiazoles via diazotization is not generally applicable to aminothiophenes. A substantially improved experimental protocol for the preparation of the title compounds as a potential inducer of systemic acquired resistance in plants is reported based on a novel cyclization mechanism via a Huisgen-White type rearrangement.