22737-33-3 Usage
Description
N-METHYL-N,O-BIS(TRIMETHYLSILYL)HYDROXYLAMINE is a chemical compound that serves as a versatile reagent in organic synthesis. It is known for its ability to convert aldehydes and ketones into N-methyl nitrones with high regioand chemoselectivity. Additionally, it can be used as a source of methylnitrene through pyrolysis and as a source of the trimethylsilyl(methyl)aminyl radical through photolysis. N-METHYL-N,O-BIS(TRIMETHYLSILYL)HYDROXYLAMINE has a boiling point of 40-41 °C at 10 mmHg and a refractive index of 1.4146.2.
Uses
Used in Organic Synthesis:
N-METHYL-N,O-BIS(TRIMETHYLSILYL)HYDROXYLAMINE is used as a reagent for converting aldehydes and ketones to N-methyl nitrones with high regioand chemoselectivity. This selective conversion is valuable in the synthesis of various organic compounds and pharmaceuticals.
Used as a Source of Methylnitrene:
In pyrolysis reactions, N-METHYL-N,O-BIS(TRIMETHYLSILYL)HYDROXYLAMINE can serve as a source of methylnitrene, a highly reactive intermediate that can be used in the synthesis of various nitrogen-containing compounds.
Used as a Source of the Trimethylsilyl(methyl)aminyl Radical:
Photolysis of N-METHYL-N,O-BIS(TRIMETHYLSILYL)HYDROXYLAMINE generates the trimethylsilyl(methyl)aminyl radical, which can be employed in various radical reactions and processes in organic chemistry.
Used in Chemical Research:
Due to its unique properties and reactivity, N-METHYL-N,O-BIS(TRIMETHYLSILYL)HYDROXYLAMINE is also used in chemical research to explore new reaction pathways, develop novel synthetic methods, and study the behavior of reactive intermediates.
Preparation
It is obtained in 52% yield by reaction of Nmethylhydroxylamine
with chlorotrimethylsilane (2.0 equiv)
and triethylamine (3.3 equiv) in ether at 25 °C.
Check Digit Verification of cas no
The CAS Registry Mumber 22737-33-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,7,3 and 7 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 22737-33:
(7*2)+(6*2)+(5*7)+(4*3)+(3*7)+(2*3)+(1*3)=103
103 % 10 = 3
So 22737-33-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H21NOSi2/c1-8(10(2,3)4)9-11(5,6)7/h1-7H3
