22751-16-2Relevant articles and documents
Engineered Biosynthesis of Fungal 4-Quinolone Natural Products
Liu, Mengting,Ohashi, Masao,Tang, Yi
supporting information, p. 6637 - 6641 (2020/09/02)
Quinolone-containing natural products are widely found in bacteria, fungi, and plants. The fungal quinolactacins, which are N-methyl-4-quinolones, display a wide spectrum of biological activities. Here we uncovered a concise nonribosomal peptide synthetase pathway involved in quinolactacin A biosynthesis from Penicillium by using heterologous reconstitution and in vitro enzymatic synthesis. The N-desmethyl analog of quinolactacin A was accessed through the construction of a hybrid bacterial and fungi pathway in the heterologous host.
NOVEL ARYL HYDROCARBON RECEPTOR LIGANDS DERIVED FROM KYNURENINE
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Paragraph 0193, (2019/05/18)
The present invention relates to novel compounds which are aryl hydrocarbon receptor (AHR) ligands and uses thereof.
The end of an old hypothesis: The pseudomonas signaling molecules 4-hydroxy-2-alkylquinolines derive from fatty acids, not 3-ketofatty acids
Dulcey, Carlos Eduardo,Dekimpe, Valérie,Fauvelle, David-Alexandre,Milot, Sylvain,Groleau, Marie-Christine,Doucet, Nicolas,Rahme, Laurence G.,Lépine, Fran?ois,Déziel, Eric
, p. 1481 - 1491 (2014/01/06)
Summary Groups of pathogenic bacteria use diffusible signals to regulate their virulence in a concerted manner. Pseudomonas aeruginosa uses 4-hydroxy-2-alkylquinolines (HAQs), including 4-hydroxy-2-heptylquinoline (HHQ) and 3,4-dihydroxy-2-heptylquinoline