22774-34-1

Basic information

• Product Name: 4-methoxy-N,N-di(prop-2-ynyl)benzenamine
• Synonyms: 4-methoxy-N,N-di(prop-2-ynyl)benzenamine
• CAS NO: 22774-34-1
• Molecular Weight: 199.252
• Mol File: 22774-34-1.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 4-methoxy-N,N-di(prop-2-ynyl)benzenamine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methoxy-N,N-di(prop-2-ynyl)benzenamine(22774-34-1)
• EPA Substance Registry System: 4-methoxy-N,N-di(prop-2-ynyl)benzenamine(22774-34-1)

Safety Data

• Hazardous Substances Data: 22774-34-1(Hazardous Substances Data)

Upstream product

• 104-94-9 4-methoxy-aniline 
• 106-96-7 propargyl bromide 
• 16156-58-4 prop-2-yn-1-ol methanesulfonate 
• 6165-75-9 propargyl benzenesulfonate 

Relevant articles and documents

Three-step pathway towards bis(1,2,3-triazolyl-γ-propylsilatranes) as Cu2+ fluorescent sensor, via 'Click Silylation'

A series of substituted aniline derivatized bis(1,2,3-triazolyl-γ- propylsilatranes) 3a-3f were designed in good yield from their triethoxysilane analogues via Cu(I) 'Click Silylation'. All the silatranes 3a-3f were characterized by IR, NMR (1H, 13C) and HRMS studies. All these compounds were explored for their thermal stability by thermogravimetric analysis (TGA)/differential thermal analysis (DTA)/differential scanning calorimetry (DSC) study and electronic properties by UV-vis spectroscopy and fluorescence study. The binding of silatranes 3a-3f to Cu2+ ion proves them to be good chemosensor. These silatranes were subjected to time dependent hydrolysis under normal atmospheric conditions. IR spectroscopic data support hydrolytic instability of 3a, 3c and 3e.

Synthesis of polyfunctional triethoxysilanes by 'click silylation'

The copper-catalyzed 'click silylation' has been exploited for the chemical modification of γ-azidopropyltriethoxysilane (AzPTES) with a wide range of terminal alkynes (1a-1v) in a one-pot operation. The novel 1,2,3-triazole-triethoxysilane derivatives (2a-2v) were synthesized by this procedure and comprehensively characterized by IR spectra, 1H and 13C NMR, and HRMS studies.

A highly efficient tandem [3 + 2] "click" cycloaddition/6-exo-cyclization strategy for the construction of triazole fused pyrazines

The pharmaceutically important tetrahydro-[1,2,3]triazolopyrazine heterocyclic architecture has been synthesized via a concise tandem "click"/6-exo-dig cyclization strategy in mixed aqueous-organic media. The generality of this mild method was expanded to various amino acid based substrates. The scopes and limitations of this method are discussed in the paper.