22774-67-0

Basic information

• Product Name: Benzenamine, 4-chloro-N-2-propynyl-
• CAS NO: 22774-67-0
• Molecular Formula: C9H8ClN
• Molecular Weight: 165.622
• Mol File: 22774-67-0.mol
• Article Data: 22

Chemical Properties

• CAS DataBase Reference: Benzenamine, 4-chloro-N-2-propynyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 4-chloro-N-2-propynyl-(22774-67-0)
• EPA Substance Registry System: Benzenamine, 4-chloro-N-2-propynyl-(22774-67-0)

Safety Data

• Hazardous Substances Data: 22774-67-0(Hazardous Substances Data)

Upstream product

• 6165-75-9 propargyl benzenesulfonate 
• 106-47-8 4-chloro-aniline 
• 1679-18-1 4-Chlorophenylboronic acid 
• 106-96-7 propargyl bromide 
• 624-65-7 2-propynyl chloride 

Downstream Products

• 111493-07-3 (4-Chloro-phenyl)-prop-2-ynyl-carbamic acid ethyl ester 
• 612-57-7 6-chloroquinoline 
• 13519-80-7 N-allyl-4-chloroaniline 
• 13179-30-1 methyl 1-(4-chlorophenyl)-1H-pyrrole-2-carboxylate 
• 60011-73-6 N-benzo-p-chloranilid 

Relevant articles and documents

One-pot, two-step synthesis of 7-methylene-1,5-piperazine-fused 1,2,3-triazoles

A facile, one-pot two-step synthesis of 7-methylene-1,5-piperazine-fused 1,2,3-triazole derivatives has been developed. The protocol employs an N-allylation of N-propargylated amines with 2,3-dibromopropene in the presence of K2CO3 in DMSO and a CuI-catalyzed [3 + 2] cycloaddition reaction of the synthetic N-(2-bromoallyl)-N-propargyl amines with sodium azide sequentially. Such a method provides methylene-substituted 1,2,3-triazole fused piperazines with some advantages such as simple operation, high efficiency and good product yield (80–91%) through readily available starting materials.

Stereoselective Synthesis of Hexahydroimidazo[1,2- a]quinolines via SN2-Type Ring-Opening Hydroarylation-Hydroamination Cascade Cyclization of Activated Aziridines with N-Propargylanilines

A novel synthetic approach for the construction of 1,2,3,3a,4,5-hexahydroimidazo[1,2-a]quinolines in good yields (up to 75%) with excellent stereoselectivity (dr up to 94:6, ee up to >99%) under one-pot domino ring-opening cyclization (DROC) conditions ha

Zinc(ii)-catalyzed intramolecular hydroarylation-redox cross-dehydrogenative coupling of N -propargylanilines with diverse carbon pronucleophiles: Facile access to functionalized tetrahydroquinolines

Zinc(ii)-catalyzed intramolecular hydroarylation-redox cross-dehydrogenative coupling of N-propargylanilines with two types of carbon pronucleophiles (nitromethane as a sp3 carbon pronucleophile and phenylacetylenes as sp carbon pronucleophiles) proceeded to give the 2-substituted tetrahydroquinolines in good yields with 100percent atomic utilization without any additional external oxidants.