2278-10-6 Usage
Description
(3Z,5E)-4-hydroxy-6-phenylhexa-3,5-dien-2-one, also known as curcumin diacetate, is a chemical compound derived from the turmeric plant. It is a member of the curcuminoid family, known for its antioxidant and anti-inflammatory properties. With a yellow-orange color, it is commonly used as a coloring agent in food and cosmetics. Studies suggest that it may have potential therapeutic effects against various diseases, such as cancer, diabetes, arthritis, and Alzheimer's disease. It is considered safe for consumption in small amounts and is often used as a dietary supplement.
Uses
Used in Food Industry:
(3Z,5E)-4-hydroxy-6-phenylhexa-3,5-dien-2-one is used as a coloring agent for its yellow-orange hue, enhancing the visual appeal of various food products.
Used in Cosmetic Industry:
In cosmetics, (3Z,5E)-4-hydroxy-6-phenylhexa-3,5-dien-2-one serves as a natural coloring agent, providing a vibrant shade to products while also offering potential health benefits due to its antioxidant properties.
Used in Pharmaceutical Industry:
(3Z,5E)-4-hydroxy-6-phenylhexa-3,5-dien-2-one is used as a potential therapeutic agent for its antioxidant and anti-inflammatory properties, with studies suggesting its effectiveness against diseases such as cancer, diabetes, arthritis, and Alzheimer's disease.
Used as a Dietary Supplement:
Due to its safety for consumption in small amounts and potential health benefits, (3Z,5E)-4-hydroxy-6-phenylhexa-3,5-dien-2-one is often used as a dietary supplement to support overall health and well-being.
Check Digit Verification of cas no
The CAS Registry Mumber 2278-10-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,2,7 and 8 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 2278-10:
(6*2)+(5*2)+(4*7)+(3*8)+(2*1)+(1*0)=76
76 % 10 = 6
So 2278-10-6 is a valid CAS Registry Number.
2278-10-6Relevant articles and documents
2-Hydroxycurcuminoid induces apoptosis of human tumor cells through the reactive oxygen species-mitochondria pathway
Han, Young-Min,Shin, Dae-Seop,Lee, Yu-Jin,Ismail, Ismail Ahmed,Hong, Su-Hyung,Han, Dong Cho,Kwon, Byoung-Mog
scheme or table, p. 747 - 751 (2011/03/18)
2-Hydroxycinnamaldehyde (HCA) and curcumin have been reported to have antitumor effects against various human tumor cells in vitro and in vivo by generation of ROS. Aldehyde-free HCA analogs were synthesized based on the structure of curcumin, which we have called 2-hydroxycurcuminoids. The hydroxyl group of curcuminoids enhances the ability to generate ROS. 2-Hydroxycurcuminoid (HCC-7) strongly inhibited the growth of SW620 colon tumor cells with a GI 50 value of 7 μM, while the parent compounds, HCA and curcumin, displayed GI50 values of 12 and 30 μM, respectively. HCC-7 was found to induce apoptosis through the reactive oxygen species-mitochondria pathway and cell cycle arrest at G2/M phase.
