22824-20-0Relevant articles and documents
Deconstructive di-functionalization of unstrained, benzo cyclic amines by C-N bond cleavage using a recyclable tungsten catalyst
Zhang, Yujing,Sun, Shuai,Su, Yijin,Zhao, Jian,Li, Yong-Hong,Han, Bo,Shi, Feng
supporting information, p. 4970 - 4974 (2019/05/29)
With H2WO4 as the catalyst and H2O2 as the oxidant, we herein report a deconstructive difunctionalization of the C-N bond in unstrained, benzo cyclic amines to generate an ester group and nitro group simultaneously. The preliminary mechanistic studies suggested that the corresponding hydroxamic acid is the key intermediate for this transformation. Importantly, with the utilization of this transformation, we achieved an interesting approach for the ring contraction of quinoline to indole, an example of scaffold hopping in a hetero-aromatic system.
Histone deacetylase inhibitors
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Page/Page column 8, (2011/12/03)
This invention relates to novel Histone deacetylases inhibitors. Also disclosed is a method for treating mucositis or cancer with these inhibitors.
Carboxylic acid derivatives, process for producing the same and drugs containing the same as the active ingredient
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, (2008/06/13)
A carboxylic acid derivative of formula (1) wherein R1 is COOH, COOR6 etc.; A is alkylene etc.; R2 is alkyl, alkenyl, alkynyl etc.; B is carbocyclic ring or heterocyclic ring; R4 is alkyl, cycloalkyl etc.; Rsup