228245-16-7Relevant articles and documents
Peptide microarrays for the determination of protease substrate specificity
Salisbury, Cleo M.,Maly, Dustin J.,Ellman, Jonathan A.
, p. 14868 - 14870 (2002)
A method is described for the preparation of substrate microarrays that allow for the rapid determination of protease substrate specificity. Peptidyl coumarin substrates, synthesized on solid support using standard techniques, are printed onto glass slide
FLUORESCENT PROBES FOR ABASIC SITE DETECTION
-
, (2016/11/02)
A fluorescent probe for binding to and detection of AP sites of DNA includes the following formula: F-L-X where F is a fluorescent moiety, X is an aminooxy group (-ONH2), and L is a linker that links or couples the fluorescent moiety to the oxy
Designer macrocyclic organo-peptide hybrids inhibit the interaction between p53 and HDM2/X by accommodating a functional α-helix
Smith, Jessica M.,Frost, John R.,Fasan, Rudi
supporting information, p. 5027 - 5030 (2014/05/06)
We report the design of side-chain-to-tail linked organo-peptide hybrids incorporating an α-helical protein-binding motif. Using this strategy, macrocyclic inhibitors of the p53:HDM2 interaction displaying dual specificity against the HDMX homolog as well
