22847-06-9

Basic information

• Product Name: 4-Ketoundecanoicacid
• Synonyms: 4-Ketoundecanoicacid
• CAS NO: 22847-06-9
• Molecular Formula: C₁₁H₂₀O₃
• Molecular Weight: 200.2747
• Mol File: 22847-06-9.mol
• Article Data: 8

Chemical Properties

• Melting Point: 77 °C
• Boiling Point: 160-164 °C(Press: 1.5 Torr)
• Appearance: /
• Density: 0.992±0.06 g/cm3(Predicted)
• PKA: 4.78±0.17(Predicted)
• CAS DataBase Reference: 4-Ketoundecanoicacid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Ketoundecanoicacid(22847-06-9)
• EPA Substance Registry System: 4-Ketoundecanoicacid(22847-06-9)

Safety Data

• Hazardous Substances Data: 22847-06-9(Hazardous Substances Data)

Upstream product

• 68676-82-4 4-oxo-undec-2t-enoic acid 
• 74568-02-8 4-hydroxyundecanoic acid 
• 22769-72-8 4-Oxoundecansaeure-ethylester 
• 32781-52-5 5-heptyl-2-oxo-2,3-dihydro-furan-3,4-dicarboxylic acid diethyl ester 
• 108-30-5 succinic acid anhydride 
• 62485-88-5 Heptylmangan(II)iodid 
• 141882-62-4 1-ethyl (+/-)-2-hexyl-3-oxohexanedioate 
• 157560-06-0 (E)-4-Nitro-undec-4-enoic acid methyl ester 
• 57681-50-2 4-hydroxy-1-undecanoic acid sodium salt 
• 104-67-6 5-heptyldihydro-2(3H)-furanone 
• 111-71-7 heptanal 
• 138286-76-7 ethyl-2-bromooctanoate 
• 4282-40-0 1-Iodoheptane 

Downstream Products

• 132959-41-2 (-)-(3R,7aS)-3-Phenyl-5-oxo-7a-heptyl-2,3,5,6,7,7a-hexahydropyrrolo<2,1-b>oxazole 
• 74568-02-8 4-hydroxyundecanoic acid 
• 104-67-6 5-heptyldihydro-2(3H)-furanone 
• 116830-36-5 (-)-N-<2-(1-Hydroxy-2(R)-phenylethyl)>-5(R)-heptyl-2-pyrrolidine 
• 139564-36-6 (+)-N-<2-(1-Hydroxy-2(R)-phenylethyl)>-5(R)-heptyl-2-pyrrolidinone 
• 74568-06-2 (R)-5-heptyl-dihydrofuran-2-one 

Relevant articles and documents

MODIFIED AMINE LIPIDS

The disclosure provides ionizable amine lipids and salts thereof (e.g., pharmaceutically acceptable salts thereof) useful for the delivery of biologically active agents, for example delivering biologically active agents to cells to prepare engineered cells. The ionizable amine lipids disclosed herein are useful as ionizable lipids in the formulation of lipid nanoparticle-based compositions.

4-Ketoundecanoic acid: [undecanoic acid, 4-oxo-]

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An Efficient Approach to β-Oxoadipate Derivatives and γ-Oxo Acids by the Reformatsky Reaction of Ethyl α-Bromoalkanoates with Succinic Anhydride

Ethyl 2-bromoalkanoates react with zinc and succinic anhydride in dimethylformamide forming 2-substituted 1-ethyl hydrogen 3-oxoadipates (hexanedioates) isolable in a yield of 56 - 78percent.When subjected to decarboxylative saponification, they afford 4-oxoalkanoic acids in overall yields of 50 - 72percent